Metabolic Effects of Aerobic Training and Resistance Training in Type 2 Diabetic Subjects: A randomized controlled trial (the RAED2 study)

• Published in: Diabetes care Vol. 35; no. 4; pp. 676 - 682
• Main Authors: Bacchi, Elisabetta, Negri, Carlo, Zanolin, Maria Elisabetta, Milanese, Chiara, Faccioli, Niccolò, Trombetta, Maddalena, Zoppini, Giacomo, Cevese, Antonio, Bonadonna, Riccardo C, Schena, Federico, Bonora, Enzo, Lanza, Massimo, Moghetti, Paolo
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.04.2012
• Subjects: abdominal fat; adipose tissue; Adult; adverse effects; Aged; analysis; Biological and medical sciences; blood; Blood Glucose; Blood Glucose - analysis; Blood Glucose - metabolism; Cholesterol; Combined Modality Therapy; Dextrose; Diabetes; Diabetes Mellitus, Type 2; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - metabolism; Diabetes Mellitus, Type 2 - therapy; Diabetes. Impaired glucose tolerance; dual-energy X-ray absorptiometry; Eating; Eating - physiology; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Exercise; Exercise - physiology; Exercise Therapy; Exercise Therapy - adverse effects; Exercise Therapy - methods; Female; Glucose; glucose tolerance; glycohemoglobin; Humans; Insulin; Insulin resistance; Insulin Resistance - physiology; islets of Langerhans; magnetic resonance imaging; Male; Medical research; Medical sciences; Medicine, Experimental; Metabolic diseases; metabolism; methods; Middle Aged; Miscellaneous; multivariate analysis; noninsulin-dependent diabetes mellitus; Original Research; oxygen consumption; patients; phenotype; Physical Fitness; Physical Fitness - physiology; Physiological aspects; physiology; Public health. Hygiene; Public health. Hygiene-occupational medicine; randomized clinical trials; Resistance Training; Resistance Training - adverse effects; Resistance Training - methods; risk factors; strength training; Studies; therapy; Type 2 diabetes; Weight training; Endocrinopathy; Type 2 diabetes; Human; Resistance; Randomization; Nutrition; Randomised controlled trial; Clinical trial; Metabolic diseases; Metabolism; Endocrinology

OBJECTIVE: To assess differences between the effects of aerobic and resistance training on HbA1c (primary outcome) and several metabolic risk factors in subjects with type 2 diabetes, and to identify predictors of exercise-induced metabolic improvement. RESEARCH DESIGN AND METHODS: Type 2 diabetic p...