Real-Time Hypoglycemia Prediction Suite Using Continuous Glucose Monitoring: A safety net for the artificial pancreas

• Published in: Diabetes care Vol. 33; no. 6; pp. 1249 - 1254
• Main Authors: Dassau, Eyal, Cameron, Fraser, Lee, Hyunjin, Bequette, B. Wayne, Zisser, Howard, Jovanovič, Lois, Chase, H. Peter, Wilson, Darrell M, Buckingham, Bruce A, Doyle, Francis J. III
• Format: Journal Article
• Language: English
• Published: United States American Diabetes Association 01.06.2010
• Subjects: Adolescent; Algorithms; analysis; blood; blood glucose; Blood Glucose - analysis; Blood sugar monitoring; Child; Child, Preschool; children; data collection; Dextrose; Diabetes; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 1 - blood; Diabetes Mellitus, Type 1 - drug therapy; Diabetes therapy; drug therapy; Female; Glucose; Human powered aircraft; Humans; hypoglycemia; Hypoglycemia - blood; Hypoglycemia - drug therapy; insulin; Insulin Infusion Systems; insulin-dependent diabetes mellitus; Male; Medical research; Medicine, Experimental; monitoring; Navigation; Original Research; pancreas; Pancreas, Artificial; patients; prediction; Predictive Value of Tests

OBJECTIVE: The purpose of this study was to develop an advanced algorithm that detects pending hypoglycemia and then suspends basal insulin delivery. This approach can provide a solution to the problem of nocturnal hypoglycemia, a major concern of patients with diabetes. RESEARCH DESIGN AND METHODS:...