Diminished sarco/endoplasmic reticulum Ca²⁺ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma - Mahn, Katharina; Hirst, Stuart J; Ying, Sun; Holt, Mark R; Lavender, Paul; Ojo, Oluwaseun O; Siew, Leonard; Simcock, David E; McVicker, Clare G; Kanabar, Varsha; Snetkov, Vladimir A; O'Connor, Brian J; et al. (Proceedings of the National Academy of Sciences - PNAS, 2009)
Keywords: adenosinetriphosphatase; Asthma; Asthma - metabolism; Asthma - pathology; Asthma - physiopathology; Biological Sciences; Blotting, Western; bradykinin; Bronchi - metabolism; Bronchi - pathology; Bronchi - physiopathology; Ca2-transporting ATPase; Calcium; Calcium - metabolism; Cell culture techniques; Cell Movement; Cell Proliferation; Cells, Cultured; chemokine CCL11; Chemokine CCL11 - secretion; Cultured cells; cytosol; Female; Gene Expression Regulation, Enzymologic; Homeostasis; Humans; Immunohistochemistry; Interleukin-13 - pharmacology; Male; Messenger RNA; Myocytes, Smooth Muscle - drug effects; Myocytes, Smooth Muscle - metabolism; phenotype; Phenotypes; Protein isoforms; protein synthesis; quantitative polymerase chain reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; sarcoplasmic reticulum; Sarcoplasmic Reticulum - enzymology; Sarcoplasmic Reticulum Calcium-Transporting ATPases; secretion; Small interfering RNA; Smooth muscle; Smooth muscle myocytes; Western blotting