Ratiometric Fluorescent Probe Based on FRET for Imaging Hg²⁺ Ions in Living Cells

• Published in: Angewandte Chemie International Edition Vol. 47; no. 42; pp. 8025 - 8029
• Main Authors: Zhang, Xiaolin, Xiao, Yi, Qian, Xuhong
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley-VCH Verlag 01.01.2008; WILEY-VCH Verlag; WILEY‐VCH Verlag; Wiley
• Subjects: Cell Line, Tumor; Cell Survival; Chemistry; Chemistry, Multidisciplinary; Fluorescence Resonance Energy Transfer; Fluorescent Dyes - chemistry; fluorescent probes; FRET; Humans; Ions - analysis; Ions - chemistry; mercury; Mercury - analysis; Mercury - chemistry; Mercury - metabolism; Molecular Structure; Physical Sciences; rhodamine; Science & Technology; sensors; DESIGN; RECOGNITION; mercury; SENSOR; fluorescent probes; RESONANCE-ENERGY-TRANSFER; TURN-ON; CHEMOSENSOR; sensors; HG(II); FRET; MERCURIC ION; rhodamine; WATER; CHEMODOSIMETER

Mercury rising: A FRET‐based ratiometric probe (see picture; FRET=fluorescence resonance energy transfer) can selectively detect Hg2+ ions on the parts‐per‐billion scale under physiological conditions. The probe undergoes a clear Hg2+‐induced change in the intensity ratio of the two well‐separated a...