Abnormal liver enzymes in outpatients with eating disorders
Objective: This study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their clinical correlates. Method: Eight hundred seventy-nine eating-disordered outpatients presenting at a suburban clinic constituted...
Saved in:
| Published in | The International journal of eating disorders Vol. 20; no. 3; pp. 325 - 329 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York, NY
Wiley
01.11.1996
Wiley Subscription Services, Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0276-3478 1098-108X |
| DOI | 10.1002/(SICI)1098-108X(199611)20:3<325::AID-EAT13>3.0.CO;2-Z |
Cover
| Abstract | Objective: This study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their clinical correlates. Method: Eight hundred seventy-nine eating-disordered outpatients presenting at a suburban clinic constituted the subject population. Serum glutamic oxalacetic transaminase, serum glutamic pyruvate transaminase, and gamma glutamyl transpeptidase (SGOT, SGPT, and GGTP, respectively) were drawn at intake. Medical charts were reviewed to obtain further clinical data on all patients with an enzyme elevation. Results: Liver enzymes were abnormally high in 36 patients (4.1%). Elevated SGPT was the most frequent enzyme abnormality and was correlated with lower current and past weight and body mass index (BMI). Discussion: Hepatic dysfunction in eating-disordered outpatients is neither specific nor common. Low weight alone can cause liver damage, yet elevated liver chemistries in patients with anorexia and especially bulima are often not due to their eating disorder |
|---|---|
| AbstractList | Objective: This study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their clinical correlates. Method: Eight hundred seventy-nine eating-disordered outpatients presenting at a suburban clinic constituted the subject population. Serum glutamic oxalacetic transaminase, serum glutamic pyruvate transaminase, and gamma glutamyl transpeptidase (SGOT, SGPT, and GGTP, respectively) were drawn at intake. Medical charts were reviewed to obtain further clinical data on all patients with an enzyme elevation. Results: Liver enzymes were abnormally high in 36 patients (4.1%). Elevated SGPT was the most frequent enzyme abnormality and was correlated with lower current and past weight and body mass index (BMI). Discussion: Hepatic dysfunction in eating-disordered outpatients is neither specific nor common. Low weight alone can cause liver damage, yet elevated liver chemistries in patients with anorexia and especially bulima are often not due to their eating disorder A study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their clinical correlates. Liver enzymes were abnormally high in 36 patients, with elevated serum glutamic pyruvate transaminase being the most frequent enzyme abnormality. Objective: This study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their clinical correlates. Method: Eight hundred seventy-nine eating-disordered outpatients presenting at a suburban clinic constituted the subject population. Serum glutamic oxalacetic transaminase, serum glutamic pyruvate transaminase, and gamma glutamyl transpeptidase (SGOT, SGPT, and GGTP, respectively) were drawn at intake. Medical charts were reviewed to obtain further clinical data on all patients with an enzyme elevation. Results: Liver enzymes were abnormally high in 36 patients (4.1%). Elevated SGPT was the most frequent enzyme abnormality and was correlated with lower current and past weight and body mass index (BMI). Discussion: Hepatic dysfunction in eating-disordered outpatients is neither specific nor common. Low weight alone can cause liver damage, yet elevated liver chemistries in patients with anorexia and especially bulima are often not due to their eating disorder. This study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their clinical correlates.OBJECTIVEThis study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their clinical correlates.Eight hundred seventy-nine eating-disordered outpatients presenting at a suburban clinic constituted the subject population. Serum glutamic oxalacetic transaminase, serum glutamic pyruvate transaminase, and gamma glutamyl transpeptidase (SGOT, SGPT, and GGTP, respectively) were drawn at intake. Medical charts were reviewed to obtain further clinical data on all patients with an enzyme elevation.METHODEight hundred seventy-nine eating-disordered outpatients presenting at a suburban clinic constituted the subject population. Serum glutamic oxalacetic transaminase, serum glutamic pyruvate transaminase, and gamma glutamyl transpeptidase (SGOT, SGPT, and GGTP, respectively) were drawn at intake. Medical charts were reviewed to obtain further clinical data on all patients with an enzyme elevation.Liver enzymes were abnormally high in 36 patients (4.1%). Elevated SGPT was the most frequent enzyme abnormality and was correlated with lower current and past weight and body mass index (BMI).RESULTSLiver enzymes were abnormally high in 36 patients (4.1%). Elevated SGPT was the most frequent enzyme abnormality and was correlated with lower current and past weight and body mass index (BMI).Hepatic dysfunction in eating-disordered outpatients is neither specific nor common. Low weight alone can cause liver damage, yet elevated liver chemistries in patients with anorexia and especially bulima are often not due to their eating disorder.DISCUSSIONHepatic dysfunction in eating-disordered outpatients is neither specific nor common. Low weight alone can cause liver damage, yet elevated liver chemistries in patients with anorexia and especially bulima are often not due to their eating disorder. This study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their clinical correlates. Eight hundred seventy-nine eating-disordered outpatients presenting at a suburban clinic constituted the subject population. Serum glutamic oxalacetic transaminase, serum glutamic pyruvate transaminase, and gamma glutamyl transpeptidase (SGOT, SGPT, and GGTP, respectively) were drawn at intake. Medical charts were reviewed to obtain further clinical data on all patients with an enzyme elevation. Liver enzymes were abnormally high in 36 patients (4.1%). Elevated SGPT was the most frequent enzyme abnormality and was correlated with lower current and past weight and body mass index (BMI). Hepatic dysfunction in eating-disordered outpatients is neither specific nor common. Low weight alone can cause liver damage, yet elevated liver chemistries in patients with anorexia and especially bulima are often not due to their eating disorder. |
| Author | Quinlan, D.M Roloff, P Greenfeld, D Mickley, D. (Yale University School of Medicine, New Haven, CT.) Zwas, F |
| Author_xml | – sequence: 1 fullname: Mickley, D. (Yale University School of Medicine, New Haven, CT.) – sequence: 2 fullname: Greenfeld, D – sequence: 3 fullname: Quinlan, D.M – sequence: 4 fullname: Roloff, P – sequence: 5 fullname: Zwas, F |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3257046$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/8912046$$D View this record in MEDLINE/PubMed |
| BookMark | eNqF0V9r1EAQAPBFKvVa_QKCEESkfcg5M_s3VyscZ9WDQh_agvgS9pJNTUk2525SqZ_ehTv64IsPwzLMb4ed2SN24AfvGDtHmCMAfTi5Xq_WpwiFyRHM9xMsCoV4SrDgHznJxWK5_pxfLG-Qf-JzmK-uzij_8YzNnm4csBmQVjkX2rxgRzHeA4DiIA_ZoSmQQKgZO1tu_BB622Vd--BC5vyfx97FrPXZMI1bO7bOjzH73Y4_M5cyf5fVbRxC7UJ8yZ43tovu1f48ZrdfLm5W3_LLq6_r1fIybzjSmCuQWEtXWHISsEKuOBkludMNaVsYULXbcFlx0CSUqDCFrjc1FpTeqxQ_Zu93fbdh-DW5OJZ9GyvXdda7YYqlNpIQEP8LRRpbEZkE3_4D74cp-DRESYhIwqBI6M0eTZve1eU2tL0Nj-V-d6n-bl-3sbJdE6yv2vjE0h_pHXu9Y40dSnsXErm9LrQQgiT_C2WojQo |
| CODEN | INDIDJ |
| ContentType | Journal Article |
| Copyright | 1996 INIST-CNRS Copyright Wiley Periodicals Inc. Nov 1996 |
| Copyright_xml | – notice: 1996 INIST-CNRS – notice: Copyright Wiley Periodicals Inc. Nov 1996 |
| DBID | FBQ IQODW CGR CUY CVF ECM EIF NPM 7TS K9. 7S9 L.6 7X8 |
| DOI | 10.1002/(SICI)1098-108X(199611)20:3<325::AID-EAT13>3.0.CO;2-Z |
| DatabaseName | AGRIS Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Physical Education Index ProQuest Health & Medical Complete (Alumni) AGRICOLA AGRICOLA - Academic MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Health & Medical Complete (Alumni) Physical Education Index AGRICOLA AGRICOLA - Academic MEDLINE - Academic |
| DatabaseTitleList | ProQuest Health & Medical Complete (Alumni) AGRICOLA MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: FBQ name: AGRIS url: http://www.fao.org/agris/Centre.asp?Menu_1ID=DB&Menu_2ID=DB1&Language=EN&Content=http://www.fao.org/agris/search?Language=EN sourceTypes: Publisher |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Psychology Diet & Clinical Nutrition |
| EISSN | 1098-108X |
| EndPage | 329 |
| ExternalDocumentID | 10462787 8912046 3257046 US9744425 |
| Genre | Journal Article Feature |
| GeographicLocations | United States |
| GeographicLocations_xml | – name: United States |
| GroupedDBID | --- .3N .GA .GJ .Y3 05W 0R~ 10A 1L6 1OB 1OC 1ZS 2FS 31~ 33P 36B 3SF 3WU 4.4 41~ 4ZD 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 53G 5GY 5RE 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 85S 8UM 930 A03 A8Z AAESR AAEVG AAHHS AAHQN AAIPD AAMNL AANHP AANLZ AAONW AASGY AAWTL AAXRX AAYCA AAZKR ABCQN ABCUV ABDBF ABEML ABGFU ABIJN ABIVO ABJNI ABPVW ABQWH ABXGK ACAHQ ACBWZ ACCFJ ACCZN ACGFO ACGFS ACGOF ACHQT ACMXC ACPOU ACRPL ACSCC ACUHS ACXBN ACXQS ACYXJ ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADXAS ADZMN ADZOD AEEZP AEGXH AEIGN AEIMD AENEX AEQDE AEUYR AEYWJ AFBPY AFFNX AFFPM AFGKR AFWVQ AFZJQ AGHNM AGQPQ AGYGG AHBTC AHMBA AIACR AIAGR AITYG AIURR AIWBW AJBDE AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ASPBG ATUGU AUFTA AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BKOMP BMNLL BMXJE BNHUX BROTX BRXPI BY8 C45 CS3 D-E D-F DCZOG DPXWK DR2 DRFUL DRMAN DRSTM DU5 EAD EAP EBC EBD EBS EJD EMB EMK EMOBN EPL EPS ESX F00 F01 F04 F5P FBQ FEDTE FUBAC G-S G.N GNP GODZA H.T H.X HAOEW HBH HF~ HGLYW HHY HHZ HVGLF HZ~ IX1 J0M JPC KBYEO KQQ LATKE LAW LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M6U MEWTI MK4 MRFUL MRSTM MSFUL MSMAN MSSTM MVM MXFUL MXMAN MXSTM N04 N05 N9A NF~ NHB NNB O66 O9- OHT OIG OVD P2P P2W P2X P4D PALCI PQQKQ Q.N Q11 QB0 QRW R.K RIWAO RJQFR ROL RX1 SAMSI SUPJJ SV3 TAE TEORI TN5 TUS UB1 UHB UMC UMD UPT V2E V62 V8K W8V W99 WBKPD WH7 WHDPE WHG WIB WIH WIK WJL WOHZO WQJ WSUWO WXSBR XG1 XJT XSW XV2 YZZ Z0I ZCA ZGI ZXP ZY4 ZZTAW ~IA ~KM ~WT ABTAH IQODW YCJ AEUQT AFPWT CGR CUY CVF ECM EIF NPM RVT RWI VQA WRC YIF 7TS AAMMB ADXHL AEFGJ AGXDD AIDQK AIDYY K9. 7S9 L.6 7X8 |
| ID | FETCH-LOGICAL-f312t-6051d5e9a2e501c136328653e7f27a9806deb35c3072464c164c7dbd192006663 |
| ISSN | 0276-3478 |
| IngestDate | Fri Jul 11 00:29:39 EDT 2025 Thu Jul 10 18:12:50 EDT 2025 Sun Jul 13 04:50:36 EDT 2025 Wed Feb 19 01:15:48 EST 2025 Wed Apr 02 07:26:01 EDT 2025 Fri May 16 02:24:07 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Keywords | Human Enzyme Transferases Liver Body weight Anorexia nervosa Eating disorder Aminoacyltransferases γ-Glutamyltransferase Bulimia Body mass index Transaminases Aspartate transaminase Alanine transaminase Quantitative analysis |
| Language | English |
| License | CC BY 4.0 |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-f312t-6051d5e9a2e501c136328653e7f27a9806deb35c3072464c164c7dbd192006663 |
| Notes | S20 S30 9744425 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 |
| PMID | 8912046 |
| PQID | 211124814 |
| PQPubID | 49031 |
| PageCount | 5 |
| ParticipantIDs | proquest_miscellaneous_78521011 proquest_miscellaneous_48916228 proquest_journals_211124814 pubmed_primary_8912046 pascalfrancis_primary_3257046 fao_agris_US9744425 |
| PublicationCentury | 1900 |
| PublicationDate | 1996-11-01 |
| PublicationDateYYYYMMDD | 1996-11-01 |
| PublicationDate_xml | – month: 11 year: 1996 text: 1996-11-01 day: 01 |
| PublicationDecade | 1990 |
| PublicationPlace | New York, NY |
| PublicationPlace_xml | – name: New York, NY – name: United States – name: Hoboken |
| PublicationTitle | The International journal of eating disorders |
| PublicationTitleAlternate | Int J Eat Disord |
| PublicationYear | 1996 |
| Publisher | Wiley Wiley Subscription Services, Inc |
| Publisher_xml | – name: Wiley – name: Wiley Subscription Services, Inc |
| SSID | ssj0006305 |
| Score | 1.6239431 |
| Snippet | Objective: This study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency... This study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their... A study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their... |
| SourceID | proquest pubmed pascalfrancis fao |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | 325 |
| SubjectTerms | Adolescent adolescents Adult Adult and adolescent clinical studies ADULTE ADULTOS adults ALANINA AMINOTRANSFERASA ALANINE AMINOTRANSFERASE alanine transaminase Alanine Transaminase - metabolism aminoacyltransferases Anorexia Anorexia nervosa ASPARTATE AMINOTRANSFERASE Aspartate Aminotransferases Aspartate Aminotransferases - metabolism aspartate transaminase ASPARTATO AMINOTRANSFERASA binging Biological and medical sciences blood serum body mass index body weight Bulimia Child children diagnosis Eating behavior disorders Eating disorders ENFANT Enzymes enzymology Feeding and Eating Disorders Feeding and Eating Disorders - diagnosis Feeding and Eating Disorders - enzymology Female FOIE FONCTION PHYSIOLOGIQUE FUNCION FISIOLOGICA gamma-Glutamyltransferase gamma-Glutamyltransferase - metabolism HIGADO Humans JEUNESSE JUVENTUD Liver Liver - enzymology liver function Male Medical sciences metabolism Middle Aged NINOS patients PESO POIDS Predictive Value of Tests Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry SERUM SANGUIN Severity of Illness Index SUERO SANGUINEO TRANSFERASAS TRANSFERASE TRASTORNOS ALIMENTICIOS TROUBLE ALIMENTAIRE United States |
| Title | Abnormal liver enzymes in outpatients with eating disorders |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/8912046 https://www.proquest.com/docview/211124814 https://www.proquest.com/docview/48916228 https://www.proquest.com/docview/78521011 |
| Volume | 20 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwELfKEKgvCAoTYQz8QNGmKl1iO18dIJW2aEViwNZKFS-RkzhTpS6daPqwPfGnc46dNMAqAVIVRXYaX3znu5_t8x1CrwCBxiz1ALk5gpqMJDCkvISYFuGUAKLz3Fju6H46dU-m7OPMmTUaP2peS-s86sY3t54r-R-uQhnwVZ6S_QfOVi-FArgH_sIVOAzXv-JxP8ok5Fx0FtK7oiOym-vLwsGqs1znOmKqPr4moWF2IfdjimCbqzoonVQOlOXKYC2exK1_LA4RxmXi6sppuHDiSXXO66r063qeLdQ663Cz-HoGWldFhPyyWXkonJXtauVBKSjgpEmZSsFTalNi1aSG1lQjVQec_1DZKgQswOnz8WDcJgBfAhlw1p_JQFXQqtToAbGg52mbDuAtcAe__nhojvoTGwpHtGt1B5_b9D0xv9XbgMeuLgve-4FNLPZbzO3CiuuaO-gu8Ty10X-2CUDmUuUEW37pffRW03x0IOk9rKg9ULQeEqtH3wCVvV5F4TtF3zFQ10T3dIOAZVK-lK64fAWjMVVpVLbPcwq8M3mIHuiJCu4rqXuEGiJrIWM4Fzl-jXU02QU-LZM5tFCzsqXXj9FxKZq4EE2sRRPPM1wTTSxFEysJw5WEPUHTD6PJ4MTUeTrMlNokN2FGbCeOCDgRjmXHNnWpPO9MhZcSjwe-5SYiok4M5oQwl8UwQ4-9JEpgciERr0t30U62zMRThAFvcwYgN-U8YdzhkWDciyxKYsqSxE8N1IJeC_kFWMBweg6TYQZGx0D7v_RieKUitYRU5mhkroH2yl4N9QBahQSsPGG-zQz0sqoF3So3zHgmlutVyIBXLiH-9ic8H-AvmEgD7SpmVU1rNj_bVrGHmpsx9Rzt5N_XYh_wbR69KETwJ_9Jld4 |
| linkProvider | Wiley-Blackwell |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Abnormal+liver+enzymes+in+outpatients+with+eating+disorders&rft.jtitle=The+International+journal+of+eating+disorders&rft.au=Mickley%2C+D&rft.au=Greenfeld%2C+D&rft.au=Quinlan%2C+D+M&rft.au=Roloff%2C+P&rft.date=1996-11-01&rft.issn=0276-3478&rft.volume=20&rft.issue=3&rft.spage=325&rft_id=info:doi/10.1002%2F%28SICI%291098-108X%28199611%2920%3A3%3C325%3A%3AAID-EAT13%3E3.0.CO%3B2-Z&rft_id=info%3Apmid%2F8912046&rft.externalDocID=8912046 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0276-3478&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0276-3478&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0276-3478&client=summon |