detection of antibodies in human and animal filariases by counterimmunoelectrophoresis with Dirofilaria immitis antigens

Counterimmunoelectrophoresis revealed the presence of precipitin antibody in all of 6 dogs and the 1 cat infected with Dirofilaria immitis and in the serum of 17 of 24 individuals living in a setting of hyperendemic subperiodic bancroftian filariasis. Antigens used in the test were prepared from mic...

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Bibliographic Details
Published inJournal of helminthology Vol. 50; no. 1; pp. 53 - 57
Main Authors Desowitz, R.S, Una, S.R
Format Journal Article
LanguageEnglish
Published England 01.03.1976
Subjects
animal diseases
animal health
Animals
Antibodies - analysis
Antigens
Cat Diseases - immunology
Cats
Dirofilaria immitis - immunology
Dirofilariasis - immunology
Dirofilariasis - veterinary
Dog Diseases - immunology
Dogs
Filariasis - immunology
Filarioidea - immunology
Humans
Microfilariae - immunology
Skin Tests
Wuchereria
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Summary:Counterimmunoelectrophoresis revealed the presence of precipitin antibody in all of 6 dogs and the 1 cat infected with Dirofilaria immitis and in the serum of 17 of 24 individuals living in a setting of hyperendemic subperiodic bancroftian filariasis. Antigens used in the test were prepared from microfilariae and adult male D. immitis. Some humans and animals had antibodies to both antigens while others had antibodies against microfilariae or adult worms only. The presence of soluble circulating antigen was detected in the sera of two dogs with high microfilaraemias.
ISSN:0022-149X
1475-2697
DOI:10.1017/S0022149X00028856