Effect of Cellular Environment on the Selective Activation of the Vitamin D Receptor by 1α,25-Dihydroxyvitamin D3 and Its Analog 1α-Fluoro-16-Ene-20-Epi-23-Ene-26,27-Bishomo-25-Hydroxyvitamin D3 (Ro-26-9228)
The vitamin D analog, 1α-fluoro-16-ene-20-epi-23-ene-26,27-bishomo-25-hydroxyvitamin D3 (Ro-26-9228) is tissue selective, with a gene regulation preference for bone over duodenum in vivo. In the human osteoblast-like cells, hFOB, the vitamin D receptor (VDR)-mediated transcriptional potencies of Ro-...
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Published in | Molecular endocrinology (Baltimore, Md.) Vol. 18; no. 4; pp. 874 - 887 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Endocrine Society
01.04.2004
Oxford University Press |
Online Access | Get full text |
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