Neonatal Cytokine Profiles Associated With Autism Spectrum Disorder

• Published in: Biological psychiatry (1969) Vol. 81; no. 5; pp. 442 - 451
• Main Authors: Krakowiak, Paula, Goines, Paula E., Tancredi, Daniel J., Ashwood, Paul, Hansen, Robin L., Hertz-Picciotto, Irva, Van de Water, Judy
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2017
• Subjects: Autism spectrum disorder; Autism Spectrum Disorder - blood; Autism Spectrum Disorder - diagnosis; Autism Spectrum Disorder - immunology; Biomarkers - blood; Blood spot; Case-Control Studies; Chemokines; Child, Preschool; Cytokines - blood; Cytokines - immunology; Developmental delays; Female; Humans; Interleukin-1beta - blood; Interleukin-1beta - immunology; Interleukin-4 - blood; Interleukin-4 - immunology; Male; Neonatal cytokines; Neurodevelopment; Psychiatric/Mental Health; Severity of Illness Index; Neurodevelopment; Blood spot; Neonatal cytokines; Autism spectrum disorder; Chemokines; Developmental delays

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition that can be reliably diagnosed at age 24 months. Immunological phenomena, including skewed cytokine production, have been observed among children with ASD. Little is known about whether immune dysregulation is present before di...