Waking up Streptomyces secondary metabolism by constitutive expression of activators or genetic disruption of repressors - Aigle, Bertrand; Corre, Christophe (Methods in enzymology, 2012)
Keywords: Anti-Bacterial Agents - isolation & purification; Anti-Bacterial Agents - metabolism; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Biological Products - metabolism; Biosynthetic Pathways - genetics; Escherichia coli - genetics; Escherichia coli - metabolism; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Regulator; Genetic Engineering - methods; Macrolides - metabolism; Metabolome; Multigene Family; Peptides - genetics; Peptides - metabolism; Repressor Proteins - genetics; Repressor Proteins - metabolism; Streptomyces - genetics; Streptomyces - metabolism; Transcription Factors - genetics; Transcription Factors - metabolism; Transcriptional Activation