Use of O44 as a solvent for silicone oil adhesions on intraocular lenses

To describe a solvent that removes silicone oil adhesions on intraocular lenses (IOLs). The solvent O44 is a partially fluorinated alcane that dissolves silicone oil. Silicone oil adhesions on silicone and poly(methyl methacrylate) IOLs were treated with O44. The extent of silicone oil adhesions and...

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Bibliographic Details
Published inJournal of cataract and refractive surgery Vol. 25; no. 10; pp. 1392 - 1393
Main Authors Hoerauf, Hans, Menz, Dirk-Henning, Dresp, Joachim, Laqua, Horst
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.10.1999
Elsevier Science
Subjects
Biological and medical sciences
Hydrocarbons, Fluorinated - therapeutic use
Lenses, Intraocular
Medical sciences
Octanes - therapeutic use
Pilot Projects
Polymethyl Methacrylate - metabolism
Silicone Oils - metabolism
Solvents - therapeutic use
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Technology. Biomaterials. Equipments
Human
Treatment
Silicone oil
Biomaterial
Intraocular lens
Adhesion
Siloxane polymer
Solvent
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Summary:To describe a solvent that removes silicone oil adhesions on intraocular lenses (IOLs). The solvent O44 is a partially fluorinated alcane that dissolves silicone oil. Silicone oil adhesions on silicone and poly(methyl methacrylate) IOLs were treated with O44. The extent of silicone oil adhesions and the effectiveness of O44 were studied by gross microscopy. The solvent O44 removed silicone oil adhesions from both IOL types. The substance O44 may be a successful intraoperative tool to remove silicone oil IOL adhesions, avoiding IOL explantation.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0886-3350
1873-4502
DOI:10.1016/S0886-3350(99)00206-0