Carbonylation reactions: 7. Regioselective synthesis of 2-arylpropionic acids by catalytic carbonylation of styrene derivatives in the presence of palladium compounds: the critical role of the counter anion

• Published in: Journal of molecular catalysis. A, Chemical Vol. 143; no. 1; pp. 131 - 136
• Main Authors: Bonnet, Michel C., Monteiro, Adriano L., Tkatchenko, Igor
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 1999; Elsevier [1995, Vol. 95, n° 1-janvier 2017, vol. 426, part B]
• Subjects: 1-Phenylethanol; Alkoxycarbonylation; Catalysis; Chemical Sciences; Palladium; Styrenes; Weakly coordinating anions; Palladium; 1-Phenylethanol; Styrenes; Alkoxycarbonylation; Weakly coordinating anions

The regioselectivity of alkoxycarbonylation of 1-arylethanols catalysed by Pd/acid systems is very sensitive to the nature of the counter anion of the acid: chloride anion favours branched products while tetrafluoroborate and sulfonates anions favour linear products, the latter ones enhancing also p...