Liquid chromatography–positive ion electrospray mass spectrometry method for the quantification of citalopram in human plasma

• Published in: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Vol. 810; no. 2; pp. 235 - 244
• Main Authors: Pistos, Constantinos, Panderi, Irene, Atta-Politou, Julia
• Format: Journal Article
• Language: English; Japanese
• Published: Elsevier B.V 25.10.2004
• Subjects: Citalopram; Electrospray ionization; High-performance liquid chromatography; Imipramine; Mass spectrometry; Imipramine; High-performance liquid chromatography; Mass spectrometry; Electrospray ionization; Citalopram

A rapid, sensitive and novel narrow-bore liquid chromatography–mass spectrometric method was developed and fully validated for the quantification of citalopram in human plasma. The analyte and internal standard (imipramine) were extracted by liquid–liquid extraction with a mixture of hexane–heptane–...