Interleukin 10: Bridging the chasms in the immune landscape of multiple myeloma

• Published in: International review of cell and molecular biology Vol. 391; pp. 199 - 222
• Main Authors: Fernandes, Queenie, Ansari, Abdul W., Makni-Maalej, Karama, Merhi, Maysaloun, Dermime, Said, Ahmad, Aamir, Uddin, Shahab
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 2025
• Subjects: Animals; Humans; Il-10, Circulatory biomarkers; Immunotherapy; Interleukin-10 - immunology; Interleukin-10 - metabolism; Multiple myeloma; Multiple Myeloma - immunology; Multiple Myeloma - pathology; Tumor Microenvironment - immunology; Immunotherapy; Il-10, Circulatory biomarkers; Multiple myeloma

[Display omitted] Multiple myeloma (MM) is a complex hematologic malignancy characterized by the abnormal proliferation of plasma cells in the bone marrow, leading to significant clinical challenges and a high burden of morbidity and mortality. Interleukin 10 (IL-10), a cytokine with potent anti-inf...