Copper homeostasis in Streptococcus and Neisseria: Known knowns and unknown knowns

• Published in: Advances in microbial physiology Vol. 86; pp. 99 - 140
• Main Authors: Howell, Archie, Chogule, Safa, Djoko, Karrera Y.
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 2025
• Subjects: Animals; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Copper - metabolism; Copper homeostasis; Copper sensing; Copper transport; Homeostasis; Humans; Mouth - microbiology; Neisseria; Neisseria - genetics; Neisseria - metabolism; Streptococcus; Streptococcus - genetics; Streptococcus - metabolism; Copper sensing; Copper transport; Copper homeostasis; Streptococcus; Neisseria

Our research group studies copper (Cu) homeostasis in Streptococcus and Neisseria, with a current focus on species that colonise the human oral cavity. Our early ventures into this field very quickly revealed major differences between well-characterised Cu homeostasis systems in species with well-kn...