Development of Hf4+-immobilized polydopamine-coated magnetic graphene for highly selective enrichment of phosphopeptides

• Published in: Talanta (Oxford) Vol. 149; pp. 91 - 97
• Main Authors: Lin, Haizhu, Deng, Chunhui
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.03.2016
• Subjects: biocompatibility; blood serum; graphene; Hafnium; humans; hydrophilicity; IMAC; iron oxides; MALDI; phosphopeptides; Phosphopeptides enrichment; Polydopamine; skim milk; surface area; Polydopamine; IMAC; Phosphopeptides enrichment; MALDI; Hafnium

In this work, we first designed and synthesized an IMAC material with Hf4+ immobilized on polydopamine-coated magnetic graphene and applied it to phosphopeptides enrichment successfully. The newly prepared material gathered the advantages of large specific surface area of graphene, good hydrophilici...