C5a- and Tumor Necrosis Factor-α-Induced Leukocytosis Occurs Independently of β2 Integrins and L-Selectin: Differential Effects on Neutrophil Adhesion Molecule Expression In Vivo

• Published in: Blood Vol. 85; no. 10; pp. 2900 - 2909
• Main Authors: Jagels, Mark A., Chambers, J.David, Arfors, Karl-E., Hugli, Tony E.
• Format: Journal Article
• Language: English
• Published: Washington, DC Elsevier Inc 15.05.1995; The Americain Society of Hematology
• Subjects: Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Immunobiology; Myeloid cells: ontogeny, maturation, markers, receptors; Polynuclears; Vertebrata; Mammalia; Integrin; Leukocytosis; Cell adhesion molecule; Rabbit; Exploration; Neutrophil; Lagomorpha

We previously demonstrated in rabbits that various neutrophil chemotactic factors share an ability to induce recruitment of polymorphonuclear leukocytes (PMN) from bone marrow when administered intravenously (Jagels and Hugli, J Immunol 148:1119, 1992). In the study reported here, we investigated th...