Stimulation by calmodulin of Ca 2+ uptake and (Ca 2+-Mg 2+) ATPase activity in membrane fractions from ox neurohypophyses
Calmodulin stimulated 45Ca 2+ uptake into a plasma membrane enriched fraction from ox neurohypophysial nerve endings and into a microsome fraction. The 45Ca 2+ uptake and the (Ca 2+-Mg 2+) ATPase activity in the plasma membrane fraction exhibited similar pCa and calmodulin sensitivities, suggesting...
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Published in | Cell calcium (Edinburgh) Vol. 2; no. 2; pp. 125 - 136 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier India Pvt Ltd
1981
|
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Abstract | Calmodulin stimulated
45Ca
2+ uptake into a plasma membrane enriched fraction from ox neurohypophysial nerve endings and into a microsome fraction. The
45Ca
2+ uptake and the (Ca
2+-Mg
2+) ATPase activity in the plasma membrane fraction exhibited similar pCa and calmodulin sensitivities, suggesting that the enzyme activity is the biochemical expression of a high affinity Ca
2+ pump. Calmodulin thus seems to play a role in regulation of the intracellular free Ca
2+ concentration in the neurohypophysis. |
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AbstractList | Calmodulin stimulated
45Ca
2+ uptake into a plasma membrane enriched fraction from ox neurohypophysial nerve endings and into a microsome fraction. The
45Ca
2+ uptake and the (Ca
2+-Mg
2+) ATPase activity in the plasma membrane fraction exhibited similar pCa and calmodulin sensitivities, suggesting that the enzyme activity is the biochemical expression of a high affinity Ca
2+ pump. Calmodulin thus seems to play a role in regulation of the intracellular free Ca
2+ concentration in the neurohypophysis. |
Author | Særmark, T. Conigrave, A.D. Thorn, N.A. Treiman, M. |
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ContentType | Journal Article |
Copyright | 1981 |
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DOI | 10.1016/0143-4160(81)90029-4 |
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References | Sobue, Ichida, Yoshida, Yamazaki, Kakiuchi (BIB5) 1979; 99 Sillén, mantell (BIB7) 1971 Ross (BIB15) 1979 Russell, Thorn (BIB1) 1975; 93 Torp-Pedersen, Treiman, Thorn (BIB8) 1979; 32 Alonso, Assenmacher (BIB19) 1979; 99 Katz, Repke, Dunnett, Hasselbach (BIB17) 1977; 252 Torp-Pedersen, Særmark, Bundgaard, Thorn (BIB2) 1980; 35 Sheaves, Hope (BIB20) 1980; 356 Russell, Thorn (BIB3) 1977; 491 Muallem, Karlish, Law (BIB14) 1979 Dartt, Torp-Pedersen, Thorn (BIB21) 1980; 204 Pershadsingh, McDaniel, Landt, Bry, Lacy, McDonald (BIB10) 1980; 288 Wolff, Poirier, Brostrom, Brostrom (BIB9) 1977; 252 Lopachuk, Richter, Katz (BIB12) 1980; 19 Flodgaard, Torp-Pedersen (BIB6) 1978; 171 Waisman, Gimble, Goodman, Rasmussen (BIB11) 1981; 256 Vilhardt, Baker, Hope (BIB4) 1975; 148 Larsen, Vincenzi (BIB13) 1979; 204 McGraw, Somlyo, Blaustein (BIB18) 1980; 85 Eroglu, Keen (BIB16) 1977; 29 |
References_xml | – volume: 35 start-page: 552 year: 1980 end-page: 557 ident: BIB2 article-title: ATP-dependent Ca publication-title: Journal of Neurochemistry contributor: fullname: Thorn – volume: 288 start-page: 492 year: 1980 end-page: 495 ident: BIB10 article-title: Ca publication-title: Nature contributor: fullname: McDonald – volume: 204 start-page: 121 year: 1980 end-page: 128 ident: BIB21 article-title: Effects of Ca publication-title: Brain Research contributor: fullname: Thorn – volume: 491 start-page: 398 year: 1977 end-page: 408 ident: BIB3 article-title: Isolation and purification of calcium-binding proteins from bovine neurohypophyses publication-title: Biochimica et Biophysica Acta contributor: fullname: Thorn – year: 1971 ident: BIB7 publication-title: Stability constants of metal-ion complexes contributor: fullname: mantell – start-page: 66 year: 1979 ident: BIB14 article-title: A red cell like Ca pump in brain microsomes publication-title: Abstract VII. Meeting of the International Society of Neurochemistry contributor: fullname: Law – volume: 32 start-page: 1085 year: 1979 end-page: 1091 ident: BIB8 article-title: Subcellular distribution of cyclic AMP phosphodiesterase in the ox neurohypophysis publication-title: Journal of Neurochemistry contributor: fullname: Thorn – volume: 356 start-page: 435 year: 1980 ident: BIB20 article-title: Calmodulin and neurosecretion publication-title: Calmodulin and Cell function contributor: fullname: Hope – volume: 19 start-page: 5603 year: 1980 end-page: 5607 ident: BIB12 article-title: Characterization of calmodulin effects on calcium transport in cardiac microsomes enriched in sacroplasmic reticulum publication-title: Biochemistry contributor: fullname: Katz – volume: 99 start-page: 199 year: 1979 end-page: 202 ident: BIB5 article-title: Occurrence of a Ca publication-title: FEBS Letters contributor: fullname: Kakiuchi – volume: 204 start-page: 306 year: 1979 end-page: 309 ident: BIB13 article-title: Calcium transport across the plasma membrane: Stimulation by calmodulin publication-title: Science contributor: fullname: Vincenzi – volume: 93 start-page: 364 year: 1975 end-page: 377 ident: BIB1 article-title: Adenosine triphosphate dependent calcium uptake by subcellular fractions from bovine neurohypophyses publication-title: Acta Physiologica Scandinavica contributor: fullname: Thorn – volume: 85 start-page: 228 year: 1980 end-page: 241 ident: BIB18 article-title: Localization of calcium in presynaptic nerve terminals publication-title: Journal of Cell Biology contributor: fullname: Blaustein – volume: 171 start-page: 817 year: 1978 end-page: 820 ident: BIB6 article-title: A calcium ion-dependent adenosine triphosphate pyrophosphohydrolase in plasma membrane from rat liver publication-title: Biochemical Journal contributor: fullname: Torp-Pedersen – start-page: 69 year: 1979 ident: BIB15 article-title: Regulation of synaptosomal Ca publication-title: Abstract VII. Meeting of the International Society of Neurochemistry contributor: fullname: Ross – volume: 256 start-page: 409 year: 1981 end-page: 414 ident: BIB11 article-title: Studies of the Ca publication-title: Journal of Biological Chemistry contributor: fullname: Rasmussen – volume: 252 start-page: 4108 year: 1977 end-page: 4117 ident: BIB9 article-title: Divalent cation binding properties of bovine brain Ca publication-title: Journal of Biological Chemistry contributor: fullname: Brostrom – volume: 252 start-page: 1950 year: 1977 end-page: 1956 ident: BIB17 article-title: Dependence of calcium permeability of sarcoplasmic reticulum vesicles on external and internal calcium ion concentrations publication-title: Journal of Biological Chemistry contributor: fullname: Hasselbach – volume: 99 start-page: 415 year: 1979 end-page: 429 ident: BIB19 article-title: The smooth endoplasmic reticulum in neurohypophysial axons of the rat: possible involvement in transport, storage and release of neurosecretory material publication-title: Cell Tissue Research contributor: fullname: Assenmacher – volume: 29 start-page: 905 year: 1977 end-page: 909 ident: BIB16 article-title: Active uptake of publication-title: Journal of Neurochemistry contributor: fullname: Keen – volume: 148 start-page: 57 year: 1975 end-page: 65 ident: BIB4 article-title: Isolation and protein composition of membranes of neurosecretory vesicles and plasma membranes from the neural lobe of the bovine pituitary gland publication-title: Biochemical Journal contributor: fullname: Hope |
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Snippet | Calmodulin stimulated
45Ca
2+ uptake into a plasma membrane enriched fraction from ox neurohypophysial nerve endings and into a microsome fraction. The
45Ca
2+... |
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StartPage | 125 |
Title | Stimulation by calmodulin of Ca 2+ uptake and (Ca 2+-Mg 2+) ATPase activity in membrane fractions from ox neurohypophyses |
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