The influence of peroxisome proliferator-activated receptor γ 1 during differentiation of mouse embryonic stem cells to neural cells

• Published in: Differentiation (London) Vol. 83; no. 1; pp. 60 - 67
• Main Authors: Ghoochani, Ali, Shabani, Khadijeh, Peymani, Maryam, Ghaedi, Kamran, Karamali, Fereshteh, Karbalaei, Khadijeh, Tanhaie, Somayeh, Salamian, Ahmad, Esmaeili, Abolghasem, Valian-Borujeni, Sadegh, Hashemi, Mehrdad, Nasr-Esfahani, Mohammad Hossein, Baharvand, Hossein
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 2012
• Subjects: Embryonic stem cells; Neural differentiation; PPARγ; Retinoic acid; BADGE; Neural differentiation; DMSO; CNS; DAPI; mESCs; Embryonic stem cells; RXR; PPARs; PPARγ; RA; NPs; FITC; Map2; TZDs; PPRE; EBs; MIAMAI; ANF; KDMEM; TRITC; Retinoic acid; NSC

Peroxisome proliferator activated receptor γ, belongs to PPARs, which exerts various metabolic functions including differentiation process. To testify the importance of PPARγ in neural differentiation of mouse embryonic stem cells (mESCs), its expression level was assessed. Data revealed an elevatio...