Ex vivo gene therapy with adenovirus-mediated transforming growth factor β 1 expression for endovascular treatment of aneurysm: results in a canine bilateral aneurysm model

• Published in: Journal of vascular surgery Vol. 38; no. 3; pp. 576 - 583
• Main Authors: Ribourtout, Edith, Desfaits, Anne-Cécile, Salazkin, Igor, Raymond, Jean
• Format: Journal Article
• Language: English
• Published: Mosby, Inc 2003

Endovascular treatment of cerebral aneurysm is safe and effective, but recurrence of disease is frequent compared with results with surgery. The purpose of this study was to determine the effects of recombinant transforming growth factor β 1 (rTGFβ 1) secreted by transplanted autologous vascular smo...