Regulation of the specific release of arachidonic acid by cytosolic phospholipase A 2

• Published in: Prostaglandins, leukotrienes and essential fatty acids Vol. 70; no. 4; pp. 373 - 376
• Main Author: Leslie, Christina C
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 2004

Cytosolic phospholipase A 2 alpha (cPLA 2 α) is the only PLA 2 that exhibits specificity for sn-2 arachidonic acid consistent with its primary role in mediating the agonist-induced release of arachidonic acid for eicosanoid production. It is subject to complex mechanisms of regulation that ensure th...