卒中后抑郁脑网络的研究进展
卒中后抑郁(post-stroke depression,PSD)是卒中后最常见的精神并发症,有近三分之一的卒中幸存者会罹惠PSD.目前越来越多的证据支持脑网络的异常改变是导致PSD的神经生理病理基础.卒中局部病变不仅导致特定局部脑网络(情感网络、默认网络、突显网络、记忆控制网络等)发生重构,而且还可引发全脑脑网络拓扑结构的重塑.部分卒中患者在脑网络重塑过程中,情感相关的网络发生了特征性重构,最终导致脑功能的失常出现了临床抑郁症状,导致PSD的发生.本文就PSD的脑网络研究的最新进展进行综述,以探讨PSD的发病机制....
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| Published in | Zhongguo cuzhong zazhi Vol. 15; no. 5; pp. 477 - 483 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
南方科技大学第一附属医院)神经内科,深圳 深圳市人民医院(暨南大学第二临床医学院,518020
01.05.2020
Editorial Department of Chinese Journal of Stroke |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1673-5765 |
| DOI | 10.3969/j.issn.1673-5765.2020.05.004 |
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| Abstract | 卒中后抑郁(post-stroke depression,PSD)是卒中后最常见的精神并发症,有近三分之一的卒中幸存者会罹惠PSD.目前越来越多的证据支持脑网络的异常改变是导致PSD的神经生理病理基础.卒中局部病变不仅导致特定局部脑网络(情感网络、默认网络、突显网络、记忆控制网络等)发生重构,而且还可引发全脑脑网络拓扑结构的重塑.部分卒中患者在脑网络重塑过程中,情感相关的网络发生了特征性重构,最终导致脑功能的失常出现了临床抑郁症状,导致PSD的发生.本文就PSD的脑网络研究的最新进展进行综述,以探讨PSD的发病机制. |
|---|---|
| AbstractList | 卒中后抑郁(post-stroke depression,PSD)是卒中后最常见的精神并发症,有近三分之一的卒中幸存者会罹惠PSD.目前越来越多的证据支持脑网络的异常改变是导致PSD的神经生理病理基础.卒中局部病变不仅导致特定局部脑网络(情感网络、默认网络、突显网络、记忆控制网络等)发生重构,而且还可引发全脑脑网络拓扑结构的重塑.部分卒中患者在脑网络重塑过程中,情感相关的网络发生了特征性重构,最终导致脑功能的失常出现了临床抑郁症状,导致PSD的发生.本文就PSD的脑网络研究的最新进展进行综述,以探讨PSD的发病机制. |
| Author | 王倩 党鸽 郭毅 李在望 韩晶 |
| AuthorAffiliation | 南方科技大学第一附属医院)神经内科,深圳 深圳市人民医院(暨南大学第二临床医学院,518020 |
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| Author_FL | LI Zai-wang HAN Jing GUO Yi DANG Ge WANG Qian |
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| Title | 卒中后抑郁脑网络的研究进展 |
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