脑微出血与阿尔茨海默病关系的研究进展

脑微出血(cerebral microbleeds,CMBs)是直径为2～10?mm的圆形或椭圆形低密度病变,病灶周围无水肿,经T2*梯度回波或SWI检查可以被发现,是脑小血管病的一种病理改变.随着影像学技术的发展,CMBs在阿尔茨海默病(Alzheimer's disease,AD)中的检出率不断升高.AD患者CMBs发生率高于健康人群及痴呆症患者,且主要分布在脑叶.CMBs可以通过参与颅内淀粉样变性和神经元变性,与载脂蛋白E基因产生关联及影响血脑屏障等方式在AD疾病进展中发挥作用....

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Published inZhongguo cuzhong zazhi Vol. 16; no. 4; pp. 326 - 330
Main Authors 廖艺斐, 张慧, 邹良玉
Format Journal Article
LanguageChinese
Published 深圳 518020 暨南大学第二临床医学院(深圳市人民医院,南方科技大学第一附属医院)神经内科 01.04.2021
Editorial Department of Chinese Journal of Stroke
Subjects
脑微出血，阿尔茨海默病，认知功能
阿尔茨海默病
认知功能
脑微出血
Online AccessGet full text
ISSN1673-5765
DOI10.3969/j.issn.1673-5765.2021.04.002

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Abstract 脑微出血(cerebral microbleeds,CMBs)是直径为2～10?mm的圆形或椭圆形低密度病变,病灶周围无水肿,经T2*梯度回波或SWI检查可以被发现,是脑小血管病的一种病理改变.随着影像学技术的发展,CMBs在阿尔茨海默病(Alzheimer's disease,AD)中的检出率不断升高.AD患者CMBs发生率高于健康人群及痴呆症患者,且主要分布在脑叶.CMBs可以通过参与颅内淀粉样变性和神经元变性,与载脂蛋白E基因产生关联及影响血脑屏障等方式在AD疾病进展中发挥作用.
AbstractList 脑微出血(cerebral microbleeds,CMBs)是直径为2～10?mm的圆形或椭圆形低密度病变,病灶周围无水肿,经T2*梯度回波或SWI检查可以被发现,是脑小血管病的一种病理改变.随着影像学技术的发展,CMBs在阿尔茨海默病(Alzheimer's disease,AD)中的检出率不断升高.AD患者CMBs发生率高于健康人群及痴呆症患者,且主要分布在脑叶.CMBs可以通过参与颅内淀粉样变性和神经元变性,与载脂蛋白E基因产生关联及影响血脑屏障等方式在AD疾病进展中发挥作用.
Author 廖艺斐
张慧
邹良玉
AuthorAffiliation 深圳 518020 暨南大学第二临床医学院(深圳市人民医院,南方科技大学第一附属医院)神经内科
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ZHANG Hui
ZOU Liang-Yu
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认知功能
脑微出血
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Snippet 脑微出血(cerebral microbleeds,CMBs)是直径为2～10?mm的圆形或椭圆形低密度病变,病灶周围无水肿,经T2*梯度回波或SWI检查可以被发现,是脑小血管病的一种病理改变.随着影像学技术的发展,CMBs在阿尔茨海默病(Alzheimer's...
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StartPage 326
SubjectTerms 脑微出血，阿尔茨海默病，认知功能
Title 脑微出血与阿尔茨海默病关系的研究进展
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