Effect of Surgical Excision Combined with Brachytherapy Treatment on Sarcoma Surrounding Important Nerve and Blood Vessels

• Published in: Zhongliu fangzhi yanjiu Vol. 46; no. 8; pp. 729 - 732
• Main Authors: Zhang, Chao, Wang, Guowen, Han, Xiuxin, Teng, Sheng, Ma, Yulin, Chen, Zhongjie, Sun, Wujun
• Format: Journal Article
• Language: Chinese
• Published: Tianjin China Anti-Cancer Association 01.08.2019; Magazine House of Cancer Research on Prevention and Treatment
• Subjects: Blood vessels; Brachytherapy; Complications; Nonunion; Patients; Radiation therapy; Sarcoma; Surgery; Tumors
• ISSN: 1000-8578; 1000-8578
• DOI: 10.3971/j.issn.1000-8578.2019.18.1685

Objective To analyze the efficacy and safety of surgical excision combined with brachytherapy treatment on sarcoma surrounding important nerve and blood vessels. Methods We retrospectively analyzed 30 patients pathologically diagnosed as sarcoma which was adjacent to the important nerve and blood vessels from March 2015 to April 2017. Extensive resection was performed. All patients received brachytherapy 2-3 days after operation. The fractional dose was 4Gy. The total dose of radiotherapy was 40Gy, twice a day. Brachytherapy took 5 days. All patients were assessed with MSTS function before surgery and 6 months after treatment. Results The follow-up time was 18-43 months, with an average of 31 months. The median follow-up time was 32.10 months. The 2-year survival rate was 96.7%, 18 cases(60%) of surgical margin R0 and 12 cases(40%) of R1. The MSTS score was 23.36±1.51 before operation and 21.51±1.82 six months after operation(P>0.05). The local control rate of tumors was 93.3%. One patient died and one patien