EMP1 Induces Proliferation and Migration of Pancreatic Cancer Cells by Activating PI3K/AKT Signaling Pathway

• Published in: Zhongliu fangzhi yanjiu Vol. 52; no. 3; pp. 193 - 200
• Main Authors: He, Ru, Liu, Xinru, Jiang, Wenkai, Zhou, Wence
• Format: Journal Article
• Language: Chinese; English
• Published: Tianjin China Anti-Cancer Association 01.03.2025; Magazine House of Cancer Research on Prevention and Treatment
• Subjects: 1-Phosphatidylinositol 3-kinase; AKT protein; Cancer; Cell migration; Cell proliferation; Cholecystokinin; emp1; Molecular modelling; Pancreatic cancer; pi3k/akt; Scratch tests; Signal transduction; Transfection; Tumors

Objective To investigate the biological behavior of EMP1 in pancreatic cancer cells and the molecular mechanism of EMP1 in promoting tumor progression. Methods A stable EMP1 knockdown cell line was obtained by lentivirus transfection. The effect of EMP1 on the proliferation of cancer cells was deter...