The impact of Duration of Untreated Psychosis on functioning and quality of life over one year of Coordinated Specialty Care (CSC)

• Published in: PloS one Vol. 20; no. 2; p. e0312740
• Main Authors: Hazan, Hadar, Tayfur, Sümeyra N, Zhou, Bin, Li, Fangyong, Gibbs-Dean, Toni, Karmani, Sneha, Kline, Emily, Ferrara, Maria, Corbera, Silvia, Riley, Sarah, Yoviene Sykes, Laura A, Tek, Cenk, Keshavan, Matcheri S, Srihari, Vinod H
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 10.02.2025; Public Library of Science (PLoS)
• Subjects: Achievement tests; Biology and Life Sciences; Care and treatment; Community Psychiatry - methods; Community Psychiatry - statistics & numerical data; Covariance matrix; Diagnosis; Education; Employment; Employment - psychology; Employment - statistics & numerical data; Female; Follow-Up Studies; Generalized linear models; Health aspects; Humans; Labor force; Male; Medicine and Health Sciences; Mental disorders; Non-Randomized Controlled Trials as Topic; Patients; Psychological aspects; Psychoses; Psychosis; Psychosocial Functioning; Psychotic Disorders - diagnosis; Psychotic Disorders - psychology; Psychotic Disorders - therapy; Quality of life; Quality of Life - psychology; Recovery of function; Research and Analysis Methods; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - therapy; Severity of Illness Index; Social Interaction; Social Sciences; Statistical models; Time Factors; Time measurement; Trends; Unemployment; United States; Young Adult; United States; United States > US; Massachusetts
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0312740

This study examined the relationship between the Duration of Untreated Psychosis (DUP) and functional outcomes at baseline, 6 months, and 12 months after admission to Coordinated Specialty Care (CSC). A total of 246 participants from two U.S. public-sector CSC programs were categorized into Low and...