Time since last birth and the risk of endometrial cancer: A meta-analysis of observational studies

• Published in: PloS one Vol. 20; no. 7; p. e0325907
• Main Authors: Gu, Juan, Lai, Yuchen, Shou, Huafeng, Wang, Liping
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.07.2025; Public Library of Science (PLoS)
• Subjects: Adenocarcinoma; Bias; Biology and Life Sciences; Birth; Cancer; Case-Control Studies; Childbirth; Childbirth & labor; Cohort analysis; Endometrial cancer; Endometrial Neoplasms - epidemiology; Endometrial Neoplasms - etiology; Endometrium; Estrogens; Female; Genital tract; Health aspects; Health risks; Heterogeneity; Humans; Influence; Longitudinal studies; Medicine and Health Sciences; Meta-analysis; Observational studies; Observational Studies as Topic; Physical Sciences; Population studies; Pregnancy; Prevention; Research and Analysis Methods; Risk Factors; Risk management; Risk reduction; Science Policy; Sensitivity analysis; Software; Statistical analysis; Time Factors; Uterine cancer; China

Endometrial cancer, an adenocarcinoma originating from the uterine lining, is the most prevalent cancer of the female genital tract globally.Identifying early risk factors for endometrial cancer is crucial for prevention.Prior research suggests that pregnancy may lower endometrial cancer risk by red...