Geogenomic Segregation and Temporal Trends of Human Pathogenic Escherichia coli O157:H7, Washington, USA, 2005-2014

• Published in: Emerging infectious diseases Vol. 24; no. 1; pp. 32 - 39
• Main Authors: Tarr, Gillian A.M, Shringi, Smriti, Phipps, Amanda I, Besser, Thomas E, Mayer, Jonathan, Oltean, Hanna N, Wakefield, Jon, Tarr, Phillip I, Rabinowitz, Peter
• Format: Journal Article
• Language: English
• Published: U.S. National Center for Infectious Diseases 01.01.2018; Centers for Disease Control and Prevention
• Subjects: Analysis; bacteria; Escherichia coli; Escherichia coli O157; Geogenomic Segregation and Temporal Trends of Human Pathogenic; Health aspects; Infection; Phylogeny; phylogeography; Shiga-toxigenic Escherichia coli; spatial analysis; Washington; Canada; Japan

The often-noted and persistent increased incidence of Escherichia coli O157:H7 infections in rural areas is not well understood. We used a cohort of E. coli O157:H7 cases reported in Washington, USA, during 2005–2014, along with phylogenomic characterization of the infecting isolates, to identify ge...