Gene network analysis identifies dysregulated pathways in an autism spectrum disorder caused by mutations in Transcription Factor 4 - de Carvalho, Lucas M.; Carvalho, Vinicius M. A.; Camargo, Antonio P.; Papes, Fabio (Scientific reports, 2025)
Keywords: 631/114; 692/617/375/366/1373; Autism; Autism Spectrum Disorder - genetics; Autism Spectrum Disorder - metabolism; Cell adhesion; Cell differentiation; Cell interactions; Cell signaling; Co-expression analysis; Excitability; Gene Expression Profiling; Gene Regulatory Networks; Genes; Histones; Hub genes; Humanities and Social Sciences; Humans; Interactome; Molecular modelling; multidisciplinary; Mutation; Neural stem cells; Neural Stem Cells - metabolism; Neurodevelopment; Neurodevelopmental disorders; Neurons - metabolism; Organoids; Pathogenesis; Pathophysiology; Pitt–Hopkins syndrome; Progenitor cells; Science; Science (multidisciplinary); Signal Transduction; Synaptic transmission; Synaptogenesis; Transcription factors; Transcription Factors - genetics; Transcriptome; Transcriptomics; Pitt–Hopkins syndrome; Autism; Hub genes; Co-expression analysis; Interactome