Cross-species transcriptomics translation reveals a role for the unfolded protein response in Mycobacterium tuberculosis infection - Pullen, Krista M.; Finethy, Ryan; Ko, Seung-Hyun B.; Reames, Charlotte J.; Sassetti, Christopher M.; Lauffenburger, Douglas A. (NPJ systems biology and applications, 2025)
Keywords: 631/114; 631/553; Animal models; Animals; Asymptomatic; Bioinformatics; Biology; Biomedical and Life Sciences; Cell activation; Cellular stress response; Computational Biology/Bioinformatics; Computer Appl. in Life Sciences; Disease; Disease Models, Animal; Gene Expression Profiling - methods; Genotype & phenotype; Humans; Infections; Inflammatory bowel disease; Life Sciences; Macrophages; Macrophages - metabolism; Macrophages - microbiology; Mathematical models; Mice; Mycobacterium tuberculosis; Mycobacterium tuberculosis - genetics; Mycobacterium tuberculosis - pathogenicity; Pathophysiology; Phenotypes; Phenotypic variations; Protein folding; Proteins; Species Specificity; Systems Biology; Transcriptome - genetics; Transcriptomics; Tuberculosis; Tuberculosis - genetics; Tuberculosis - immunology; Tuberculosis - microbiology; Unfolded Protein Response - genetics