Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite - Bryant, Jessica M; Baumgarten, Sebastian; Dingli, Florent; Loew, Damarys; Sinha, Ameya; Claës, Aurélie; Preiser, Peter R; Dedon, Peter C; Scherf, Artur (Molecular systems biology, 2020)
Keywords: Adenosine Triphosphatases - metabolism; Animals; Antigens, Protozoan - genetics; Antigens, Protozoan - metabolism; Chromatin; Chromatin Immunoprecipitation Sequencing; Chromosomes; CRISPR; CRISPR-Cas Systems; Deoxyribonucleic acid; Divergence; DNA; EMBO09; EMBO23; Enrichment; Epigenetics; Erythrocytes; Genes; Genomes; Genomics; Humans; Immune system; Introns; Life Sciences; Malaria; Mass Spectrometry; Mass spectroscopy; Microbiology and Parasitology; MORC protein; Parasites; Parasitology; Pathogenesis; Plasmodium falciparum; Plasmodium falciparum - genetics; Plasmodium falciparum - immunology; Plasmodium falciparum - pathogenicity; Promoter Regions, Genetic; Protein Interaction Maps; Proteins; Proteomics; Proteomics - methods; Regulatory sequences; Structural proteins; Transcription activation; Transcription factors; Transcription Factors - metabolism; Var gene; var genes; Vector-borne diseases; Virulence; Virulence Factors - genetics; Virulence Factors - metabolism; CRISPR; chromatin; genes; epigenetics; Plasmodium falciparum; var genes; Virology & Host Pathogen Interaction; Microbiology; var genes Subject Categories Chromatin; Transcription & Genomics