A Novel Antibacterial Membrane Electrode Based on Bacterial Cellulose/Polyaniline/AgNO3 Composite for Bio-Potential Signal Monitoring

• Published in: IEEE journal of translational engineering in health and medicine Vol. 6; pp. 1 - 10
• Main Authors: Nannan Zhang, Lina Yue, Yajie Xie, Samuel, Oluwarotimi William, Omisore, Olatunji Mumini, Weihua Pei, Xiao Xing, Chuang Lin, Yudong Zheng, Lei Wang
• Format: Journal Article
• Language: English
• Published: New York IEEE 01.01.2018; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Accuracy; Antibacterial activity; Bacteria; bacterial cellulose/polyaniline/AgNO₃ nanocomposite membrane (BC/PANI/AgNO₃); bio-potential signal monitoring; Biomembranes; Cellulose; Coliforms; Contact potentials; E coli; Echocardiography; Electrocardiography; Electrodes; Flexible and dry electrodes; Impedance; low and stable contact impedance; Microorganisms; Monitoring; Nanocomposites; Nanofibers; Polyanilines; Qualitative analysis; Signal monitoring; Silver chloride; Skin; Substrates; Thin films; Waveforms
• DOI: 10.1109/JTEHM.2018.2863388
• ISSN: 2168-2372

We propose a flexible, dry, and antibacterial electrode with a low and stable skin electrode contact impedance for bio-potential signal monitoring. We fabricated a bacterial cellulose/polyaniline/AgNO 3 nanocomposite membrane (BC/PANI/AgNO 3 ) and used it for bio-potential signal monitoring. The bacterial cellulose (BC) provides a 3-D nanoporous network structure, and it was used as a substrate material in the BC/PANI/AgNO 3 nanocomposite membrane. Polyaniline (PANI) and AgNO 3 , acting as conductive and antibacterial components, respectively, were polymerized and deposited on the surfaces of BC nanofibers to produce uniform thin film membrane with flexible, antibacterial, and conductive properties. Various measurements were conducted, in terms of antibacterial activity, skin electrode contact impedance, and qualitative analysis of ECG signal recordings. The BC/PANI/AgNO 3 membrane revealed 100% antibacterial activities against both the Staphylococcus aureus and Escherichia coli bacteria. The skin electrode contact impedance of the proposed BC/PANI/AgNO 3 electrode is lower than that of the Ag/AgCl gel electrode, with the same active area. In addition, the electrocardiogram (ECG) signals acquired with the proposed electrodes have stable characteristic waveforms, and they are not contaminated by noise. The waveform fidelity of the BC/PANI/AgNO 3 membrane electrodes over 800 ECG cardiac cycles is 99.49%, and after the electrodes were worn for 24 hours, a fidelity of 98.40% was recorded over the same number of cardiac cycles. With the low and stable skin electrode contact impedance, the proposed dry BC/PANI/AgNO 3 membrane electrode provided high fidelity for ECG signal recordings, thus offering a potential approach for bio-potential signal monitoring. With the above benefits, the novel flexible and dry BC/PANI/AgNO 3 electrode has a significant antibacterial. Most of all, it is the first research to develop antibacterial in the electrode design.