Determinants of outcome in patients eligible for thrombolysis for ischemic stroke
Eligibility criteria for thrombolysis in ischemic stroke have been clearly defined. However, not all eligible patients benefit from this treatment. This study aimed to assess the determinants for clinical outcome in consecutive, eligible patients with ischemic stroke treated with thrombolysis in a s...
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Published in | Vascular health and risk management Vol. 3; no. 5; pp. 749 - 754 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
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New Zealand
Taylor & Francis Ltd
2007
Dove Medical Press |
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Abstract | Eligibility criteria for thrombolysis in ischemic stroke have been clearly defined. However, not all eligible patients benefit from this treatment. This study aimed to assess the determinants for clinical outcome in consecutive, eligible patients with ischemic stroke treated with thrombolysis in a single-center study.
Consecutive patients with ischemic stroke were treated with tissue plasminogen activator (t-PA) following the established eligibility National Institute of Neurological Disorders and Stroke (NINDS) and European Stroke Initiative (EUSI) criteria. Risk factors including blood pressure and pre-treatment glycemia were properly managed. Death and disability at 3 months were the study outcomes. Disability was evaluated by the Rankin-scale. Favorable outcome was defined as 0-2 and adverse outcome as 3-6 including death.
Seventy-eight patients were included in the study in a single stroke unit. The mean age was 70.9 +/- 13.2 years (range 36-94). Follow-up at 3 months was completed in 73 patients. A favorable outcome was observed in 37 patients (50%) and adverse outcome in 36 (36%). Nine patients (12.3%) died within 3 months. The presence of an occluded carotid artery was a strong predictor for adverse outcome (p < 0.0001). A low NIH Stroke Scale-Score (NIHSS) at admission was a associated with a favorable outcome, while history of diabetes mellitus led to an unfavorable outcome.
Among patients eligible for thrombolysis, many do not benefit from this treatment. These include patients with carotid occlusion and diabetes. |
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AbstractList | Objectives:Eligibility criteria for thrombolysis in ischemic stroke have been clearly defined. However, not all eligible patients benefit from this treatment. This study aimed to assess the determinants for clinical outcome in consecutive, eligible patients with ischemic stroke treated with thrombolysis in a single-center study. Methods: Consecutive patients with ischemic stroke were treated with tissue plasminogen activator (t-PA) following the established eligibility National Institute of Neurological Disorders and Stroke (NINDS) and European Stroke Initiative (EUSI) criteria. Risk factors including blood pressure and pre-treatment glycemia were properly managed. Death and disability at 3 months were the study outcomes. Disability was evaluated by the Rankin-scale. Favorable outcome was defined as 0–2 and adverse outcome as 3–6 including death. Results: Seventy-eight patients were included in the study in a single stroke unit. The mean age was 70.9 ± 13.2 years (range 36–94). Follow-up at 3 months was completed in 73 patients. A favorable outcome was observed in 37 patients (50%) and adverse outcome in 36 (36%). Nine patients (12.3%) died within 3 months. The presence of an occluded carotid artery was a strong predictor for adverse outcome (p > 0.0001). A low NIH Stroke Scale-Score (NIHSS) at admission was a associated with a favorable outcome, while history of diabetes mellitus led to an unfavorable outcome. Conclusion: Among patients eligible for thrombolysis, many do not benefit from this treatment. These include patients with carotid occlusion and diabetes. Eligibility criteria for thrombolysis in ischemic stroke have been clearly defined. However, not all eligible patients benefit from this treatment. This study aimed to assess the determinants for clinical outcome in consecutive, eligible patients with ischemic stroke treated with thrombolysis in a single-center study. Consecutive patients with ischemic stroke were treated with tissue plasminogen activator (t-PA) following the established eligibility National Institute of Neurological Disorders and Stroke (NINDS) and European Stroke Initiative (EUSI) criteria. Risk factors including blood pressure and pre-treatment glycemia were properly managed. Death and disability at 3 months were the study outcomes. Disability was evaluated by the Rankin-scale. Favorable outcome was defined as 0-2 and adverse outcome as 3-6 including death. Seventy-eight patients were included in the study in a single stroke unit. The mean age was 70.9 +/- 13.2 years (range 36-94). Follow-up at 3 months was completed in 73 patients. A favorable outcome was observed in 37 patients (50%) and adverse outcome in 36 (36%). Nine patients (12.3%) died within 3 months. The presence of an occluded carotid artery was a strong predictor for adverse outcome (p < 0.0001). A low NIH Stroke Scale-Score (NIHSS) at admission was a associated with a favorable outcome, while history of diabetes mellitus led to an unfavorable outcome. Among patients eligible for thrombolysis, many do not benefit from this treatment. These include patients with carotid occlusion and diabetes. OBJECTIVESEligibility criteria for thrombolysis in ischemic stroke have been clearly defined. However, not all eligible patients benefit from this treatment. This study aimed to assess the determinants for clinical outcome in consecutive, eligible patients with ischemic stroke treated with thrombolysis in a single-center study. METHODSConsecutive patients with ischemic stroke were treated with tissue plasminogen activator (t-PA) following the established eligibility National Institute of Neurological Disorders and Stroke (NINDS) and European Stroke Initiative (EUSI) criteria. Risk factors including blood pressure and pre-treatment glycemia were properly managed. Death and disability at 3 months were the study outcomes. Disability was evaluated by the Rankin-scale. Favorable outcome was defined as 0-2 and adverse outcome as 3-6 including death. RESULTSSeventy-eight patients were included in the study in a single stroke unit. The mean age was 70.9 +/- 13.2 years (range 36-94). Follow-up at 3 months was completed in 73 patients. A favorable outcome was observed in 37 patients (50%) and adverse outcome in 36 (36%). Nine patients (12.3%) died within 3 months. The presence of an occluded carotid artery was a strong predictor for adverse outcome (p < 0.0001). A low NIH Stroke Scale-Score (NIHSS) at admission was a associated with a favorable outcome, while history of diabetes mellitus led to an unfavorable outcome. CONCLUSIONAmong patients eligible for thrombolysis, many do not benefit from this treatment. These include patients with carotid occlusion and diabetes. Valeria Caso, Maurizio Paciaroni, Michele Venti, Francesco Palmerini, Giorgio Silvestrelli, Paolo Milia, Sergio Biagini, Giancarlo AgnelliStroke Unit, Department of Internal Medicine, Ospedale Silvestrini Perugia, ItalyObjectives: Eligibility criteria for thrombolysis in ischemic stroke have been clearly defined. However, not all eligible patients benefit from this treatment. This study aimed to assess the determinants for clinical outcome in consecutive, eligible patients with ischemic stroke treated with thrombolysis in a single-center study.Methods: Consecutive patients with ischemic stroke were treated with tissue plasminogen activator (t-PA) following the established eligibility National Institute of Neurological Disorders and Stroke (NINDS) and European Stroke Initiative (EUSI) criteria. Risk factors including blood pressure and pre-treatment glycemia were properly managed. Death and disability at 3 months were the study outcomes. Disability was evaluated by the Rankin-scale. Favorable outcome was defined as 0-2 and adverse outcome as 3-6 including death.Results: Seventy-eight patients were included in the study in a single stroke unit. The mean age was 70.9 ± 13.2 years (range 36-94). Follow-up at 3 months was completed in 73 patients. A favorable outcome was observed in 37 patients (50%) and adverse outcome in 36 (36%). Nine patients (12.3%) died within 3 months. The presence of an occluded carotid artery was a strong predictor for adverse outcome (p> 0.0001). A low NIH Stroke Scale-Score (NIHSS) at admission was a associated with a favorable outcome, while history of diabetes mellitus led to an unfavorable outcome.Conclusion: Among patients eligible for thrombolysis, many do not benefit from this treatment. These include patients with carotid occlusion and diabetes.Keywords: thrombolysis, stroke, outcome, diabetes, carotid artery occlusion Objectives Eligibility criteria for thrombolysis in ischemic stroke have been clearly defined. However, not all eligible patients benefit from this treatment. This study aimed to assess the determinants for clinical outcome in consecutive, eligible patients with ischemic stroke treated with thrombolysis in a single-center study. Methods Consecutive patients with ischemic stroke were treated with tissue plasminogen activator (t-PA) following the established eligibility National Institute of Neurological Disorders and Stroke (NINDS) and European Stroke Initiative (EUSI) criteria. Risk factors including blood pressure and pre-treatment glycemia were properly managed. Death and disability at 3 months were the study outcomes. Disability was evaluated by the Rankin-scale. Favorable outcome was defined as 0a2 and adverse outcome as 3a6 including death. Results Seventy-eight patients were included in the study in a single stroke unit. The mean age was 70.9 A- 13.2 years (range 36a94). Follow-up at 3 months was completed in 73 patients. A favorable outcome was observed in 37 patients (50%) and adverse outcome in 36 (36%). Nine patients (12.3%) died within 3 months. The presence of an occluded carotid artery was a strong predictor for adverse outcome (p & 0.0001). A low NIH Stroke Scale-Score (NIHSS) at admission was a associated with a favorable outcome, while history of diabetes mellitus led to an unfavorable outcome. Conclusion Among patients eligible for thrombolysis, many do not benefit from this treatment. These include patients with carotid occlusion and diabetes. |
Author | Agnelli, Giancarlo Silvestrelli, Giorgio Venti, Michele Paciaroni, Maurizio Milia, Paolo Palmerini, Francesco Caso, Valeria Biagini, Sergio |
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References | 10703776 - JAMA. 2000 Mar 1;283(9):1145-50 9707190 - Stroke. 1998 Aug;29(8):1544-9 11502916 - Neurology. 2001 Aug 14;57(3):474-80 12855832 - Stroke. 2003 Aug;34(8):1833-40 10209350 - Eur J Neurol. 1999 Jan;6(1):51-5 10532643 - Neurology. 1999;53(7 Suppl 4):S3-14 16505004 - J Neurol Neurosurg Psychiatry. 2006 Jul;77(7):826-9 12221155 - Neurology. 2002 Sep 10;59(5):669-74 15883405 - CMAJ. 2005 May 10;172(10):1307-12 10971019 - Cerebrovasc Dis. 2000 Sep-Oct;10(5):335-51 2727536 - Rev Neurol (Paris). 1989;145(2):134-9 2730378 - Arch Neurol. 1989 Jun;46(6):660-2 11939889 - Arch Neurol. 2002 Apr;59(4):549-53 12140674 - J Neurol. 2002 Jul;249(7):888-95 11559501 - AJNR Am J Neuroradiol. 2001 Sep;22(8):1534-42 8929152 - Arch Neurol. 1996 Apr;53(4):309-15 10657408 - Stroke. 2000 Feb;31(2):370-5 7563451 - JAMA. 1995 Oct 4;274(13):1017-25 10591384 - JAMA. 1999 Dec 1;282(21):2019-26 11546993 - Crit Care Med. 2001 Sep;29(9):1812-8 15494581 - JAMA. 2004 Oct 20;292(15):1839-44 7886712 - Stroke. 1995 Mar;26(3):392-8 16107357 - J Neurol Neurosurg Psychiatry. 2005 Sep;76(9):1234-7 9836764 - Stroke. 1998 Dec;29(12):2529-40 1642475 - Ann Neurol. 1992 Jul;32(1):78-86 12154264 - Stroke. 2002 Aug;33(8):2066-71 1579252 - Neurology. 1992 May;42(5):976-82 7477192 - N Engl J Med. 1995 Dec 14;333(24):1581-7 10067786 - J Hypertens. 1999 Feb;17(2):151-83 15494580 - JAMA. 2004 Oct 20;292(15):1831-8 7678184 - Stroke. 1993 Jan;24(1):35-41 14584488 - Cerebrovasc Dis. 2003;16(4):311-37 3363593 - Stroke. 1988 May;19(5):604-7 15016487 - Lancet. 2004 Mar 6;363(9411):768-74 9788453 - Lancet. 1998 Oct 17;352(9136):1245-51 |
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SubjectTerms | Adult Aged Aged, 80 and over Brain Ischemia - drug therapy Brain Ischemia - epidemiology Diabetes Female Humans Male Middle Aged Multivariate Analysis Original Research Risk Factors Stroke Stroke - drug therapy Stroke - epidemiology Thrombolytic Therapy Treatment Outcome |
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Title | Determinants of outcome in patients eligible for thrombolysis for ischemic stroke |
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