Solving a bottleneck in animal models of Peyronie's disease

• Published in: Asian journal of andrology Vol. 16; no. 4; p. 639
• Main Authors: Cellek, Selim, Stebbeds, William, Ralph, David J
• Format: Journal Article
• Language: English
• Published: China Medknow Publications & Media Pvt. Ltd 01.07.2014; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Animals; Disease Models, Animal; Growth factors; Invited; Male; Ossification, Heterotopic - pathology; Penile Erection - physiology; Penile Induration - pathology; Penis - pathology

Previous models used injections of transforming growth factor-beta [1] or fibrin [2] and surgical trauma to TA; [3] however, neither significant curvature nor ossification was achieved.