Disease Ontology: improving and unifying disease annotations across species

• Published in: Disease models & mechanisms Vol. 11; no. 3
• Main Authors: Bello, Susan M, Shimoyama, Mary, Mitraka, Elvira, Laulederkind, Stanley J F, Smith, Cynthia L, Eppig, Janan T, Schriml, Lynn M
• Format: Journal Article
• Language: English
• Published: England The Company of Biologists Ltd 01.03.2018; The Company of Biologists
• Subjects: Animals; Annotations; Databases, Genetic; Disease - genetics; Disease models; Gene Ontology; Genes; Genomes; Medical research; Medical Subject Headings-MeSH; Mice; Molecular Sequence Annotation; Mouse; Ontologies; Ontology; Parkinson's disease; Rat; Rats; Resource; Species Specificity; Terminology; Tumors; Ontologies; Disease models; Mouse; Rat

Model organisms are vital to uncovering the mechanisms of human disease and developing new therapeutic tools. Researchers collecting and integrating relevant model organism and/or human data often apply disparate terminologies (vocabularies and ontologies), making comparisons and inferences difficul...