High‐intensity interval training improves cardiomyocyte contractile function and myofilament sensitivity to intracellular Ca2+ in obese rats

• Published in: Experimental physiology Vol. 109; no. 10; pp. 1710 - 1727
• Main Authors: dos Santos, Matheus Corteletti, da Silva, Daniel Sesana, Cordeiro, Jóctan Pimentel, Domingos, Lucas Furtado, da Silva Gomes, Ezio Henrique, Nogueira, Breno Valentim, Bocalini, Danilo Sales, Lima Leopoldo, Ana Paula, Leopoldo, André Soares
• Format: Journal Article
• Language: English
• Published: Oxford John Wiley & Sons, Inc 01.10.2024; John Wiley and Sons Inc; Wiley
• Subjects: Adipose tissue; Calcium (intracellular); calcium handling; Calcium influx; Cardiac muscle; cardiac remodelling; Cardiomyocytes; Fibrosis; High fat diet; high‐intensity interval training; Interval training; Intracellular; Muscle contraction; Obesity; Oxygen consumption; Risk factors; Skeletal muscle

High‐intensity interval training (HIIT) has shown significant results in addressing adiposity and risk factors associated with obesity. However, there are no studies that investigate the effects of HIIT on contractility and intracellular Ca2+ handling. The purpose of this study was to explore the im...