Scientific Opinion on the substantiation of a health claim related to Bimuno® GOS and reducing gastro‐intestinal discomfort pursuant to Article 13(5) of Regulation (EC) No 1924/2006
Following an application from Clasado Limited, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Malta, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scien...
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| Published in | EFSA journal Vol. 12; no. 7 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Wiley
01.07.2014
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1831-4732 1831-4732 |
| DOI | 10.2903/j.efsa.2014.3756 |
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| Abstract | Following an application from Clasado Limited, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Malta, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to Bimuno® GOS and reducing gastro‐intestinal discomfort. The food constituent that is the subject of the health claim, Bimuno® GOS, which is a mixture of β‐galacto‐oligosaccharides produced through conversion of lactose by enzymes from Bifidobacterium bifidum NCIMB 41171, is sufficiently characterised. The claimed effect is reducing gastro‐intestinal discomfort and is considered to be a beneficial physiological effect. The applicant did not provide any studies from which data could be used for the scientific substantiation of the claimed effect of reducing gastro‐intestinal discomfort. A cause and effect relationship has not been established between the consumption of Bimuno® GOS and reducing gastro‐intestinal discomfort. |
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| AbstractList | Following an application from Clasado Limited, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Malta, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to Bimuno® GOS and reducing gastro-intestinal discomfort. The food constituent that is the subject of the health claim, Bimuno® GOS, which is a mixture of β‑galacto-oligosaccharides produced through conversion of lactose by enzymes from Bifidobacterium bifidum NCIMB 41171, is sufficiently characterised. The claimed effect is reducing gastro-intestinal discomfort and is considered to be a beneficial physiological effect. The applicant did not provide any studies from which data could be used for the scientific substantiation of the claimed effect of reducing gastro-intestinal discomfort. A cause and effect relationship has not been established between the consumption of Bimuno® GOS and reducing gastro-intestinal discomfort. Following an application from Clasado Limited, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Malta, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to Bimuno® GOS and reducing gastro‐intestinal discomfort. The food constituent that is the subject of the health claim, Bimuno® GOS, which is a mixture of β‐galacto‐oligosaccharides produced through conversion of lactose by enzymes from Bifidobacterium bifidum NCIMB 41171, is sufficiently characterised. The claimed effect is reducing gastro‐intestinal discomfort and is considered to be a beneficial physiological effect. The applicant did not provide any studies from which data could be used for the scientific substantiation of the claimed effect of reducing gastro‐intestinal discomfort. A cause and effect relationship has not been established between the consumption of Bimuno® GOS and reducing gastro‐intestinal discomfort. |
| Author | EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) |
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| References_xml | – volume: 58 start-page: 37 year: 2009 end-page: 48 article-title: A mixture containing galactooligosaccharide, produced by the enzymic activity of , reduces serovar Typhimurium infection in mice publication-title: Journal of Medical Microbiology – volume: 9 start-page: 13 issue: 12 year: 2011 article-title: Scientific Opinion on the substantiation of a health claim related to Bimuno® GOS and reducing gastro‐intestinal discomfort pursuant to Article 13(5) of Regulation (EC) No 1924/2006 publication-title: EFSA Journal – volume: 6 start-page: 81 year: 2009 end-page: 89 article-title: Development and functional properties of Bimuno®: a second‐generation prebiotic mixture publication-title: Food Science and Technology Bulletin: Functional Foods – volume: 68 start-page: 412 year: 2005b end-page: 416 article-title: (claimed as proprietary by the applicant). Synthesis of prebiotic galactooligosaccharides using whole cells of a novel strain, NCIMB 4117 publication-title: Applied Microbiology and Biotechnology – volume: 130 start-page: 1538 year: 2006 end-page: 1551 article-title: Design of treatment trials for functional gastrointestinal disorders publication-title: Gastroenterology – volume: 59 start-page: 1428 year: 2010 end-page: 1439 article-title: Purified galactooligosaccharide derived from a mixture produced by the enzymatic activity of reduced Typhimurium adhesion and invasion and publication-title: Journal of Medical Microbiology – volume: 135 start-page: 1726 year: 2005a end-page: 1731 article-title: (claimed as proprietary by the applicant). A novel galactooligosaccharide mixture increases the bifidoabcterial population numbers in a continuous fermentation system and in the proximal colonic contents of pigs publication-title: Journal of Nutrition – volume: 64 start-page: 146 year: 2010 end-page: 152 article-title: (claimed as proprietary by the applicant). A double‐blind, placebo‐controlled, randomized human study assessing the capacity of a novel galacto‐oligosaccharide mixture in reducing travellers' diarrhoea publication-title: European Journal of Clinical Nutrition – volume: 45 start-page: II69 issue: Suppl 2 year: 1999 end-page: 77 article-title: Design of treatment trials for functional gastrointestinal disorders publication-title: Gut – volume: 29 start-page: 508 year: 2009 end-page: 518 article-title: (claimed as proprietary by the applicant). Clinical trial: the effect of a ‐galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome publication-title: Alimentary Pharmacology Therapeutics – volume: 87 start-page: 785 year: 2008 end-page: 891 article-title: (claimed as proprietary by the applicant). Prebiotic evaluation of a novel galactooligosaccharide mixture produced by the enzymatic activity of NCIMB 41171, in healthy humans: a randomised, double‐blind, crossover, placebo‐controlled intervention study publication-title: American Journal of Clinical Nutrition – volume: 88 start-page: 1438 year: 2008 end-page: 1446 article-title: (claimed as proprietary by the applicant). Modulation of the fecal microflora profile and immune function by a novel trans‐galactooligosacharide mixture (B‐GOS) in healthy elderly volunteers publication-title: American Journal of Clinical Nutrition – start-page: CD003960 year: 2007 article-title: Tegaserod for the treatment of irritable bowel syndrome and chronic constipation – volume: 17 start-page: 648 year: 2007 end-page: 656 article-title: (claimed as proprietary by the applicant). Development of a process for the production and purification of α‐ and β‐galactooligosaccharides from NCIMB 41171 publication-title: International Dairy Journal – volume: 11 start-page: 10 issue: 6 year: 2013 article-title: Scientific Opinion on the substantiation of a health claim related to Bimuno® GOS and reducing gastro‐intestinal discomfort pursuant to Article 13(5) of Regulation (EC) No 1924/2006 publication-title: EFSA Journal – year: 2013 |
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| Title | Scientific Opinion on the substantiation of a health claim related to Bimuno® GOS and reducing gastro‐intestinal discomfort pursuant to Article 13(5) of Regulation (EC) No 1924/2006 |
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