Insights Into the Chromatin Structure of Thermoplasma volcanium: Archaeal HU Regulates Alba-Mediated DNA Compaction

• Published in: Archaea (Vancouver) Vol. 2024
• Main Authors: Aycardo, Kirk Amerigo B, Prieto, Eloise I
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 14.08.2024; Hindawi Limited
• Subjects: Amino acids; Atomic force microscopy; Chromatids; Chromatin; Chromatography; Chromosomes; Compaction; Deoxyribonucleic acid; DNA; DNA binding proteins; DNA methylation; DNA structure; DNA topoisomerase; DNA-binding protein; E coli; Ethylenediaminetetraacetic acid; Folding; Genomes; Genomics; Histone H1; Histones; Microscopy; Nucleic acids; Protein expression; Protein folding; Proteins; Ribonucleic acid; RNA; RNA-binding protein; Room temperature; Thermoplasma volcanium

Archaeal species encode a diversity of chromatin proteins that play distinct roles in genome compaction. Although our understanding of the individual proteins has been growing, their contributions to higher-order folding in the archaeal chromosome remain to be explored. In this study, we investigate...