Lipopolysaccharide Core Truncation in Invasive Escherichia coli O157:H7 ATCC 43895 Impairs Flagella and Curli Biosynthesis and Reduces Cell Invasion Ability

• Published in: International journal of molecular sciences Vol. 25; no. 17; p. 9224
• Main Authors: Sheng, Haiqing, Ndeddy Aka, Robinson J, Wu, Sarah
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.09.2024
• Subjects: Animals; Antigens; Bacterial Adhesion; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Biofilms; Biofilms - growth & development; Biosynthesis; bovine host; Cattle; Cell growth; cell invasion; E coli; Epithelial Cells - metabolism; Epithelial Cells - microbiology; Escherichia coli O157 - genetics; Escherichia coli O157 - metabolism; Escherichia coli O157 - physiology; Escherichia coli Proteins - genetics; Escherichia coli Proteins - metabolism; Flagella - genetics; Flagella - metabolism; invasive E. coli O157:H7; Lipids; Lipopolysaccharides - biosynthesis; LPS core; Motility; Mutation; Pathogens; production of flagella and curli; Virulence; cell invasion; bovine host; production of flagella and curli; invasive E. coli O157:H7; LPS core

O157:H7 ( O157) is known for causing severe foodborne illnesses such as hemorrhagic colitis and hemolytic uremic syndrome. Although O157 is typically regarded as an extracellular pathogen and a weak biofilm producer, some O157 strains, including a clinical strain ATCC 43895, exhibit a notable abilit...