OESTROGENS AND PROLACTIN REGULATE MAMMARY GLAND EPITHELIAL CELL GROWTH BY MODULATION OF THE WNT SIGNAL PATHWAY

• Published in: Slovenski veterinarski zbornik Vol. 53; no. 3
• Main Authors: Jinjin Tong, Hua Zhang, Yuhong Wu, Yingxue Wang, Qingzhang Li, Yun Liu
• Format: Journal Article
• Language: English
• Published: University of Ljubljana Press (Založba Univerze v Ljubljani) 01.01.2016

Estrogen and prolactin can regulate mammary gland development and epithelial cell growth as well as lactation.  Meanwhile, the Wnt signaling pathway and subsequent upregulation of b-catenin driven by downstream target of cyclinD1 also play a role in development of mammary gland. This study aimed to...