Comparison of Carcinoembryonic Antigen Level and E-Cadherin Expression between Metastatic and Non-Metastatic Colorectal Carcinoma in RSUP, Dr. Sardjito Yogyakarta-Indonesia

• Published in: Middle East journal of cancer Vol. 14; no. 4; pp. 521 - 529
• Main Authors: Rianto Prabowo, Hendra Susanto, Nurcahya Setiawan, Imam Sofii, Agus Barmawi, Adeodatus Handaya
• Format: Journal Article
• Language: English
• Published: Shiraz University of Medical Sciences 01.10.2023
• Subjects: carcinoembryonic antigen; colorectal neoplasms; e-cadherin; neoplasm metastatic; non-metastatic

Background: WHO has reported 34,189 (8.6%) colorectal carcinoma cases out of 396,914 total cancer cases in Indonesia. Accumulated gene mutation and the environment can affect cell regulation, growth, and differentiation, impacting the methylation of tumor suppressor genes. Carcinoembryonic antigen (...