Effects of angiopoietin-like protein 3 deficiency on postprandial lipid and lipoprotein metabolism1[S]

• Published in: Journal of lipid research Vol. 57; no. 6; pp. 1097 - 1107
• Main Authors: Minicocci, Ilenia, Tikka, Anna, Poggiogalle, Eleonora, Metso, Jari, Montali, Anna, Ceci, Fabrizio, Labbadia, Giancarlo, Fontana, Mario, Di Costanzo, Alessia, Maranghi, Marianna, Rosano, Aldo, Ehnholm, Christian, Donini, Lorenzo Maria, Jauhiainen, Matti, Arca, Marcello
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.06.2016; Elsevier
• Subjects: familial combined hypolipidemia; free fatty acids; postprandial lipid metabolism; free fatty acids; postprandial lipid metabolism; familial combined hypolipidemia

The consequences of angiopoietin-like protein 3 (ANGPTL3) deficiency on postprandial lipid and lipoprotein metabolism has not been investigated in humans. We studied 7 homozygous (undetectable circulating ANGPTL3 levels) and 31 heterozygous (50% of circulating ANGPTL3 levels) subjects with familial...