结直肠癌死亡患者的肿瘤转移部位、发生率及预后
R735.3; [目的]既往有多个报道结直肠癌转移方式的研究,但尚缺少基于长期随访并以死亡作为观察终点,总结CRC转移部位、发生率以及相关生存数据的研究.[方法]本研究回顾中山大学附属第六医院373例结直肠癌死亡患者资料,统计分析肿瘤转移的部位、发生率以及生存资料.[结果]334例(89.5％)患者为肿瘤相关性死亡,肝转移率为51.5％,肺转移率为40.4％,腹膜转移率为55.7％.单纯肝、肺、腹膜转移患者数分别为27例(8％)、21例(6.3％)、63例(18.9％).单纯肺转移患者生存明显优于单纯肝转移或单纯腹膜转移(P<0.01).肝肺腹膜同时转移的患者共66例(19.7％)且预后...
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| Published in | Zhongshan da xue xue bao. Zhongshan daxue xuebao yixue kexue ban = Journal of Sun Yat-sen University. Yi xue ke xue ban Vol. 43; no. 2; pp. 289 - 296 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
中山大学附属第六医院结直肠肛门外科,广东广州510655
01.03.2022
广东省结直肠盆底疾病研究重点实验室,广东广州510655%中山大学附属第六医院病案管理科,广东广州510655%中山大学附属第六医院结直肠肛门外科,广东广州510655 Editorial Office of Journal of Sun Yat-sen University |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1672-3554 |
| DOI | 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2022.0 |
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| Abstract | R735.3; [目的]既往有多个报道结直肠癌转移方式的研究,但尚缺少基于长期随访并以死亡作为观察终点,总结CRC转移部位、发生率以及相关生存数据的研究.[方法]本研究回顾中山大学附属第六医院373例结直肠癌死亡患者资料,统计分析肿瘤转移的部位、发生率以及生存资料.[结果]334例(89.5％)患者为肿瘤相关性死亡,肝转移率为51.5％,肺转移率为40.4％,腹膜转移率为55.7％.单纯肝、肺、腹膜转移患者数分别为27例(8％)、21例(6.3％)、63例(18.9％).单纯肺转移患者生存明显优于单纯肝转移或单纯腹膜转移(P<0.01).肝肺腹膜同时转移的患者共66例(19.7％)且预后最差(P<0.01).[结论]并非所有死亡结直肠癌患者都会出现肝肺腹膜同时转移.不同患者的转移方式存在差异,并与生存相关. |
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| AbstractList | 目的既往有多个报道结直肠癌转移方式的研究，但尚缺少基于长期随访并以死亡作为观察终点，总结CRC转移部位、发生率以及相关生存数据的研究。方法本研究回顾中山大学附属第六医院373例结直肠癌死亡患者资料，统计分析肿瘤转移的部位、发生率以及生存资料。结果334例（89.5%）患者为肿瘤相关性死亡，肝转移率为51.5%，肺转移率为40.4%，腹膜转移率为55.7%。单纯肝、肺、腹膜转移患者数分别为27例（8%）、21例（6.3%）、63例（18.9%）。单纯肺转移患者生存明显优于单纯肝转移或单纯腹膜转移（P<0.01）。肝肺腹膜同时转移的患者共66例（19.7%）且预后最差（P<0.01）。结论并非所有死亡结直肠癌患者都会出现肝肺腹膜同时转移。不同患者的转移方式存在差异，并与生存相关。 R735.3; [目的]既往有多个报道结直肠癌转移方式的研究,但尚缺少基于长期随访并以死亡作为观察终点,总结CRC转移部位、发生率以及相关生存数据的研究.[方法]本研究回顾中山大学附属第六医院373例结直肠癌死亡患者资料,统计分析肿瘤转移的部位、发生率以及生存资料.[结果]334例(89.5％)患者为肿瘤相关性死亡,肝转移率为51.5％,肺转移率为40.4％,腹膜转移率为55.7％.单纯肝、肺、腹膜转移患者数分别为27例(8％)、21例(6.3％)、63例(18.9％).单纯肺转移患者生存明显优于单纯肝转移或单纯腹膜转移(P<0.01).肝肺腹膜同时转移的患者共66例(19.7％)且预后最差(P<0.01).[结论]并非所有死亡结直肠癌患者都会出现肝肺腹膜同时转移.不同患者的转移方式存在差异,并与生存相关. |
| Author | 陈晓琼 石雪彬 黄美近 谭淑云 周家铭 邬小凤 李拓阳 吴远辉 |
| AuthorAffiliation | 中山大学附属第六医院结直肠肛门外科,广东广州510655;广东省结直肠盆底疾病研究重点实验室,广东广州510655%中山大学附属第六医院病案管理科,广东广州510655%中山大学附属第六医院结直肠肛门外科,广东广州510655 |
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| Title | 结直肠癌死亡患者的肿瘤转移部位、发生率及预后 |
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