Oral tablet vaccination against SARS-CoV-2 spike boosts cross-reactive serum and mucosal neutralizing antibodies following mRNA vaccination: a phase 2 clinical trial

• Published in: The Journal of immunology (1950) Vol. 210; no. 1_Supplement; pp. 246 - 246.09
• Main Authors: johnson, susan, Jegede, Clara B, Gutierrez, Samanta, Greco, Susan, Cummings, James, Gottlieb, Keith A, Tucker, Sean N
• Format: Journal Article
• Language: English
• Published: 01.05.2023

Current SARS-CoV-2 intramuscular vaccines do not induce the breadth of immunity needed to halt the development of new variants. New strategies that elicit immunity at the site of infection could induce cross-reactive mucosal responses that decrease transmission. We developed a room-temperature stabl...