BRD4 and BET proteins regulate CD8 T cell exhaustion in mouse models of cancer

Abstract Harnessing the cytotoxic capacity of CD8 T cells is central to the efficacy of immunotherapy and has revolutionized the fight against cancer. However, despite encouraging success for select indications, immunotherapies still fail to achieve durable and effective outcomes for certain cancer...

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Bibliographic Details
Published inThe Journal of immunology (1950) Vol. 210; no. 1_Supplement; pp. 171 - 171.07
Main Authors Pratt, Brandon M, Green, William D, Mullins, Genevieve, Green, Jarred, Milner, Justin
Format Journal Article
LanguageEnglish
Published 01.05.2023
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