Primary pleural myxoid liposarcoma: case report and literature review

• Published in: International journal of research in medical sciences Vol. 10; no. 9; p. 2024
• Main Authors: Palacios R., Doris M., Castillo M., Daniel B., Ruiz P., Jose L., Silva F., Rafael
• Format: Journal Article
• Language: English
• Published: 29.08.2022
• DOI: 10.18203/2320-6012.ijrms20222282
• ISSN: 2320-6071

Myxoid liposarcoma is a histological subtype of malignant tumors within the group of sarcomas. It is more common in men between the ages of 40 and 50 years. Diagnosis is difficult because they are usually asymptomatic lesions, computed tomography (CT) scan and magnetic resonance are the studies of choice. The gold of treatment is surgical resection with free margins. Chemotherapy and radiotherapy have shown a good response. A 46-year-old male was detected incidental mediastinal lesion by radiography, CT scan showed a hypodense lesion in the right hemithorax that extended to the left hemithorax, infiltrating the diaphragm and large vessels. The patient underwent an exploratory thoracotomy, finding a multilobulated tumor and mucous content approximately 600 ml, adjacent structures were infiltrated, so complete resection was not possible. Subsequently, adjuvant chemotherapy given. The histopathological diagnosis was myxoid liposarcoma. Myxoid liposarcoma is a malignant lesion. The primary pleural origin is rare. Surgical resection with free margins has a good prognosis. Due to advanced disease, a complete resection in this case was not possible, that compromised the patient prognosis.