On the potential intermediacy of PhIBr 2 as a brominating agent

• Published in: Organic & biomolecular chemistry Vol. 20; no. 43; pp. 8454 - 8460
• Main Authors: Tania, Molino, Andrew, Sharp-Bucknall, Lachlan, Wilson, David J. D., Dutton, Jason L.
• Format: Journal Article
• Language: English
• Published: England 09.11.2022
• Subjects: Halogenation

PhIBr 2 , first purported to exist over 100 years ago, has been subject of few reports due to its low stability. However, a recent publication proposes a reaction of PIFA (PhI(OC(O)-CF 3 ) 2 ) with TMSBr to form PhIBr 2 in situ and demonstrated its efficacy in aryl brominations. This report investig...