Lumefantrine co-amorphous systems using deoxycholic acid as a co-former: NIR at-line process monitoring by machine learning

• Published in: Bio-medical materials and engineering p. 9592989251353457
• Main Authors: Otsuka, Yuta, Naitou, Kiyotada, Miyata, Takeshi
• Format: Journal Article
• Language: English
• Published: United States 04.08.2025
• Subjects: machine learning; lumefantrine; mechanochemical synthesis; co-amorphous

BackgroundVarious methods have been reported for improving the water-insoluble drugs in oral administration formulations. Among them, amorphization has been attracting attention and developed as a method for solubilizing API (active pharmaceutical ingredient)s by changing their physicochemical prope...