Distinct phenotypes of rare autoreactive and virus-reactive CD8+ T cells revealed through novel clustering algorithm

• Published in: The Journal of immunology (1950) Vol. 210; no. 1_Supplement; pp. 78 - 78.07
• Main Authors: Kus, Anna, Wiedeman, Alice, Long, Alice
• Format: Journal Article
• Language: English
• Published: 01.05.2023

Antigen-specific cells are implicated in the development and progression of disease in autoimmunity, infectious disease, and cancer, and are an attractive target for therapies. While robust detection of antigen-specific cells is possible with tetramer and activation-induced marker assays, extensive...