Molecular signatures underlying heterogenous hypertrophy responsiveness to resistance training in older men and women: a within-subject design

• Published in: Journal of applied physiology (1985)
• Main Authors: Lixandrão, Manoel E., Bamman, Marcas, Lavin, Kaleen M., Longobardi, Igor, Telles, Guilherme, Vechin, Felipe C., Damas, Felipe, Drummer, Devin J., McAdam, Jeremy S., Riani Costa, Luiz A., Libardi, Cleiton A., Gualano, Bruno, Roschel, Hamilton
• Format: Journal Article
• Language: English
• Published: 21.08.2025

We showed higher resistance training (RT) volume (4-sets) offsets muscle hypertrophy non-responsiveness to single-set RT (1-set), while enhancing hypertrophic response among responders. Here, we investigated molecular traits underpinning RT-related hypertrophic variability via targeted (ribosome den...