Co-production of hemagglutinin H9N2 influenza virus and fusion protein Newcastle virus in insect cell using baculovirus expression system

• Published in: Cellular and Molecular Biology Vol. 70; no. 8; pp. 76 - 81
• Main Authors: Moheb Shahedin, Mohaddeseh, Moghbeli, Majid, Kargar, Mohammad, Forouzanfar, Mohsen
• Format: Journal Article
• Language: English
• Published: France 08.09.2024
• Subjects: Animals; Baculoviridae - genetics; Cloning, Molecular - methods; Gene Expression; Genetic Vectors - genetics; Hemagglutinin Glycoproteins, Influenza Virus - genetics; Hemagglutinin Glycoproteins, Influenza Virus - metabolism; Influenza A Virus, H9N2 Subtype - genetics; Newcastle disease virus - genetics; Sf9 Cells; Spodoptera; Viral Fusion Proteins - genetics; Viral Fusion Proteins - metabolism

Influenza and Newcastle disease are the most important poultry diseases that cause high annual damage to poultry farms worldwide. Newcastle virus fusion (F) gene and Influenza Virus Hemagglutinin (HA) gene are capable of encoding F and HA proteins that are the main factors in creating immunity, so t...